Treatment of atopic dermatitis: Recently approved drugs and advanced clinical development programs

S Müller, L Maintz, T Bieber - Allergy, 2024 - Wiley Online Library
Atopic dermatitis (AD) represents the most common skin disease characterized by
heterogeneous endophenotypes and a high disease burden. In Europe, six new systemic …

Neues in der Systemtherapie der atopischen Dermatitis

T Werfel, A Wollenberg, T Pumnea… - …, 2018 - epub.ub.uni-muenchen.de
In severe cases of atopic dermatitis (AD) systemic treatment is indicated. So far, cyclosporine
and systemic glucocorticosteroids represented the only systemic treatment options approved …

Towards personalized treatment in atopic dermatitis

J van der Schaft, JL Thijs, FM Garritsen… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: For many years, oral immunosuppressive drugs such as cyclosporine A,
azathioprine, mycophenolic acid, and methotrexate were the only treatment options, in …

[HTML][HTML] Atopic Dermatitis in Children and Adults: Diagnosis and Treatment

A Wollenberg, T Werfel, J Ring, H Ott… - Deutsches Ärzteblatt …, 2023 - ncbi.nlm.nih.gov
Background Atopic dermatitis is a common, chronically recurring inflammatory skin disease.
It gives rise to a high disease burden and is of major importance in social medicine. Methods …

[HTML][HTML] Atopic dermatitis: epidemiology and clinical phenotypes

A Raimondo, S Lembo - Dermatology practical & conceptual, 2021 - ncbi.nlm.nih.gov
Atopic dermatitis (AD) is a chronic, lifelong, relapsing condition. The wide spectrum of the
possible clinical presentations, depending on patient's age, age of onset of disease …

Atopic dermatitis: Disease features, therapeutic options, and a multidisciplinary approach

L Lugović-Mihić, J Meštrović-Štefekov, I Potočnjak… - Life, 2023 - mdpi.com
The latest findings regarding AD pathogenesis point to an impaired function of the epidermal
barrier, changed immune response, colonization of the skin by microorganisms, and certain …

Efficacy of biologics in atopic dermatitis

J Wu, E Guttman-Yassky - Expert Opinion on Biological Therapy, 2020 - Taylor & Francis
Introduction: Atopic dermatitis (AD) is a heterogeneous disease. Recent advancements in
understanding AD pathogenesis resulted in the exponential expansion of its therapeutic …

Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year …

A Blauvelt, M de Bruin-Weller, M Gooderham… - The Lancet, 2017 - thelancet.com
Background Dupilumab (an anti-interleukin-4-receptor-α monoclonal antibody) blocks
signalling of interleukin 4 and interleukin 13, type 2/Th2 cytokines implicated in numerous …

Atopic dermatitis in adults: epidemiology, risk factors, pathogenesis, clinical features, and management

OA Oninla, AO Akinkugbe, BI Otike-Odibi… - Atopic Dermatitis …, 2021 - books.google.com
Atopic dermatitis (AD) is an itchy chronic relapsing inflammatory skin condition mostly
affecting children than adults. Eczematous conditions are common worldwide with increase …

Atopic eczema: pathophysiological findings as the beginning of a new era of therapeutic options

S Traidl, T Werfel, C Traidl-Hoffmann - Allergic Diseases–From Basic …, 2021 - Springer
Atopic eczema (AE) is a chronic inflammatory disease hallmarked by intense pruritus and
eczematous lesions. It depicts one of the most common skin diseases affecting a major part …