Endocrine disrupting compounds: can they target the immune system of fish?

A Casanova-Nakayama, M Wenger, R Burki… - Marine pollution …, 2011 - Elsevier
Endocrine disruption, in particular disruption by estrogen-active compounds, has been
identified as an important ecotoxicological hazard in the aquatic environment. Research on …

The effects of estrogenic and androgenic endocrine disruptors on the immune system of fish: a review

S Milla, S Depiereux, P Kestemont - Ecotoxicology, 2011 - Springer
During the last decade, a number of studies have shown that, in addition to their classically
described reproductive function, estrogens and androgens also regulate the immune system …

Sex-specific immunomodulatory action of the environmental estrogen 17α-ethynylestradiol alongside with reproductive impairment in fish

RY Roy, DR Peterson, SI Kitamura, H Segner… - Aquatic toxicology, 2018 - Elsevier
Estrogenic endocrine disrupting chemicals (EEDCs) are present ubiquitously in sediments
and aquatic ecosystems worldwide. The detrimental impact of EEDCs on the reproduction of …

[HTML][HTML] Estrogens as immunotoxicants: 17α-ethinylestradiol exposure retards thymus development in zebrafish (Danio rerio)

L Kernen, A Phan, J Bo, EL Herzog, J Huynh… - Aquatic toxicology, 2022 - Elsevier
Estrogenic endocrine disrupting compounds (EEDCs) can cause alterations in sexual
development and reproductive function of fish. Growing evidence suggests that EEDCs can …

Endocrine disruptors in the marine environment: mechanisms of toxicity and their influence on reproductive processes in fish

A Goksøyr - Journal of Toxicology and Environmental Health, Part A, 2006 - Taylor & Francis
Recent research demonstrated how endocrine-disrupting chemicals (EDCs) may disturb
wildlife populations and possibly also represent a human health risk. Much of the focus has …

Comparative responses of molluscs and fish to environmental estrogens and an estrogenic effluent

S Jobling, D Casey, T Rodgers-Gray, J Oehlmann… - Aquatic toxicology, 2003 - Elsevier
It is now well established that there is a diverse array of chemicals discharged into the
environment that can mimic or antagonise the action of hormones. These endocrine …

Differing species responsiveness of estrogenic contaminants in fish is conferred by the ligand binding domain of the estrogen receptor

S Miyagawa, A Lange, I Hirakawa… - … science & technology, 2014 - ACS Publications
Exposure to estrogenic endocrine disrupting chemicals (EDCs) induces a range of adverse
effects, notably on reproduction and reproductive development. These responses are …

Endocrine disrupting chemicals and sexual behaviors in fish–a critical review on effects and possible consequences

M Söffker, CR Tyler - Critical reviews in toxicology, 2012 - Taylor & Francis
Endocrine disrupting chemicals (EDCs) enter aquatic ecosystems through discharged
effluents, mainly from wastewater treatment works and diffuse run off from land, and affect a …

Molecular markers of endocrine disruption in aquatic organisms

J Rotchell, G Ostrander - Journal of Toxicology and Environmental …, 2003 - Taylor & Francis
A wide range of organic contaminant compounds prevalent in the aquatic environment has
been shown to exhibit hormone-disrupting activity. The actual potency of such compounds …

Thinking outside the box: Assessing endocrine disruption in aquatic life

SM Brander - … water quality: Pollution assessment, analysis, and …, 2013 - books.google.com
Exposures to environmental concentrations of endocrine disrupting compounds are now a
known threat to both human and ecological health [1, 2]. A large body of work has …