An approach to detecting estrogenic endocrine disruption via choriogenin expression in an estuarine model fish species
SM Brander, BJ Cole, GN Cherr - Ecotoxicology, 2012 - Springer
A large body of work has established a link between endocrine disrupting compounds
(EDCs) and a number of abnormalities in fishes. However, most EDC studies use several …
(EDCs) and a number of abnormalities in fishes. However, most EDC studies use several …
Ecological risk assessment and testing for endocrine disruption in the aquatic environment
TH Hutchinson, DB Pickford - Toxicology, 2002 - Elsevier
Field observations of endocrine disruption (ED) in fish and other aquatic species have
contributed to a global effort to establish test methods for detecting ED effects in wildlife …
contributed to a global effort to establish test methods for detecting ED effects in wildlife …
Interference of endocrine disrupting chemicals with aromatase CYP19 expression or activity, and consequences for reproduction of teleost fish
Many natural and synthetic compounds present in the environment exert a number of
adverse effects on the exposed organisms, leading to endocrine disruption, for which they …
adverse effects on the exposed organisms, leading to endocrine disruption, for which they …
Transcriptome alterations in zebrafish embryos after exposure to environmental estrogens and anti-androgens can reveal endocrine disruption
V Schiller, A Wichmann, R Kriehuber, C Schäfers… - Reproductive …, 2013 - Elsevier
Exposure to environmental chemicals known as endocrine disruptors (EDs) is in many
cases associated with an unpredictable hazard for wildlife and human health. The …
cases associated with an unpredictable hazard for wildlife and human health. The …
Screening and testing for endocrine disruption in fish—biomarkers as “signposts,” not “traffic lights,” in risk assessment
Biomarkers are currently best used as mechanistic “signposts” rather than as “traffic lights” in
the environmental risk assessment of endocrine-disrupting chemicals (EDCs). In field …
the environmental risk assessment of endocrine-disrupting chemicals (EDCs). In field …
Gene expression responses in male fathead minnows exposed to binary mixtures of an estrogen and antiestrogen
Background Aquatic organisms are continuously exposed to complex mixtures of chemicals,
many of which can interfere with their endocrine system, resulting in impaired reproduction …
many of which can interfere with their endocrine system, resulting in impaired reproduction …
The estrogen receptor of the gastropod Nucella lapillus: modulation following exposure to an estrogenic effluent?
LFC Castro, C Melo, R Guillot, I Mendes, S Queirós… - Aquatic toxicology, 2007 - Elsevier
The molecular targets of estrogenic endocrine disrupting chemicals have been studied in
detail in vertebrates. The lack of basic endocrine knowledge impairs similar approaches for …
detail in vertebrates. The lack of basic endocrine knowledge impairs similar approaches for …
Bridging the gap from screening assays to estrogenic effects in fish: potential roles of multiple estrogen receptor subtypes
EE Yost, C Lee Pow, MB Hawkins… - … science & technology, 2014 - ACS Publications
This study seeks to delineate the ligand interactions that drive biomarker induction in fish
exposed to estrogenic pollutants and provide a case study on the capacity of human (h) …
exposed to estrogenic pollutants and provide a case study on the capacity of human (h) …
Identification of endocrine-disrupting effects in aquatic vertebrates and invertebrates: report from the European IDEA project
H Segner, K Caroll, M Fenske, CR Janssen… - Ecotoxicology and …, 2003 - Elsevier
The EU-funded project IDEA aimed to evaluate (a) what parameters and endpoints allow the
detection of endocrine-mediated developmental and reproductive effects of (xeno) …
detection of endocrine-mediated developmental and reproductive effects of (xeno) …
Twenty years of transcriptomics, 17alpha-ethinylestradiol, and fish
In aquatic toxicology, perhaps no pharmaceutical has been investigated more intensely than
17alpha-ethinylestradiol (EE2), the active ingredient of the birth control pill. At the turn of the …
17alpha-ethinylestradiol (EE2), the active ingredient of the birth control pill. At the turn of the …