[HTML][HTML] Novel systemic treatment modalities including immunotherapy and molecular targeted therapy for recurrent and metastatic head and neck squamous cell …
Head and neck squamous cell carcinomas (HNSCCs) are the sixth most common cancers
worldwide. More than half of patients with HNSCC eventually experience disease …
worldwide. More than half of patients with HNSCC eventually experience disease …
[HTML][HTML] Beyond EGFR inhibition: multilateral combat strategies to stop the progression of head and neck cancer
HK Byeon, M Ku, J Yang - Experimental & molecular medicine, 2019 - nature.com
Epidermal growth factor receptor (EGFR) overexpression is common in head and neck
squamous cell carcinoma. Targeted therapy specifically directed towards EGFR has been …
squamous cell carcinoma. Targeted therapy specifically directed towards EGFR has been …
Current and potential inflammation targeted therapies in head and neck cancer
F Wang, P Arun, J Friedman, Z Chen… - Current opinion in …, 2009 - Elsevier
Inflammation often exists in the tumor microenvironment and is induced by inflammatory
mediators (cytokines, chemokines, and growth factors) produced by the tumor, stroma, and …
mediators (cytokines, chemokines, and growth factors) produced by the tumor, stroma, and …
The expanding role of systemic therapy in head and neck cancer
Treatment of squamous cell carcinoma of the head and neck (SCCHN) has evolved greatly
in the last two decades, owing to the integration of chemotherapy, advances in …
in the last two decades, owing to the integration of chemotherapy, advances in …
[HTML][HTML] Therapeutic approaches for the treatment of head and neck squamous cell carcinoma–An update on clinical trials
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common non-skin
cancer with a tobacco consumption and infection with high-risk human papillomavirus (HPV) …
cancer with a tobacco consumption and infection with high-risk human papillomavirus (HPV) …
New therapies in head and neck cancer
RT Santuray, DE Johnson, JR Grandis - Trends in cancer, 2018 - cell.com
Head and neck squamous cell carcinoma (HNSCC) is a common malignancy with high rates
of mortality and morbidity. Beginning with cetuximab, investigators continue to optimize …
of mortality and morbidity. Beginning with cetuximab, investigators continue to optimize …
Applying the molecular biology and epigenetics of head and neck cancer in everyday clinical practice
CA Glazer, SS Chang, PK Ha, JA Califano - Oral oncology, 2009 - Elsevier
During the past decade, there has been a significant increase in knowledge regarding the
molecular biology and epigenetics of head and neck squamous cell carcinoma (HNSCC) …
molecular biology and epigenetics of head and neck squamous cell carcinoma (HNSCC) …
Novel prognostic clinical factors and biomarkers for outcome prediction in head and neck cancer: a systematic review
V Budach, I Tinhofer - The Lancet Oncology, 2019 - thelancet.com
Current algorithms for the clinical management of patients with squamous cell carcinoma of
the head and neck (HNSCC) are based on a stage-dependent strategy where all patients at …
the head and neck (HNSCC) are based on a stage-dependent strategy where all patients at …
The molecular landscape of head and neck cancer
CR Leemans, PJF Snijders, RH Brakenhoff - Nature Reviews Cancer, 2018 - nature.com
Head and neck squamous cell carcinomas (HNSCCs) arise in the mucosal linings of the
upper aerodigestive tract and are unexpectedly heterogeneous in nature. Classical risk …
upper aerodigestive tract and are unexpectedly heterogeneous in nature. Classical risk …
[HTML][HTML] Epigenetic modifications and head and neck cancer: implications for tumor progression and resistance to therapy
Head and neck squamous carcinoma (HNSCC) is the sixth most prevalent cancer and one
of the most aggressive malignancies worldwide. Despite continuous efforts to identify …
of the most aggressive malignancies worldwide. Despite continuous efforts to identify …