The endocannabinoid system consists of endogenous arachidonic acid derivates that
activate cannabinoid receptors. The two most prominent endocannabinoids are …

The endocannabinoid system (ECS) has emerged as one of the most relevant regulators of
energy balance. The ECS acts through two cannabinoid receptors: types 1 and 2 (CB1 and …

During the last few years, the endocannabinoid system has emerged as a highly relevant
topic in the scientific community. Many different regulatory actions have been attributed to …

The promising results obtained by clinical trials using Rimonabant to tackle visceral obesity
and related disorders recently promoted a remarkable impulse to carry out detailed …

The endocannabinoid system has recently emerged as an important regulator of energy
homeostasis, involved in the control of both appetite and peripheral fat metabolism. We …

As the incidence of obesity continues to increase, the development of effective therapies is a
high priority. The endocannabinoid system has emerged as an important influence on the …

Endocannabinoids and cannabinoid CB1 receptors are known to play a generalized role in
energy homeostasis. However, clinical trials with the first generation of CB1 blockers, now …

The endocannabinoid (EC) signaling (ECS) system involves the activation of receptors
targeted by endogenously produced ligands called endocannabinoids that trigger specific …

The crucial role of the hypothalamus in the pathogenesis of obesity is widely recognized,
while the precise molecular and cellular mechanisms involved are the focus of intense …

Context: Cannabinoid CB1 receptor blockade decreases weight and hyperinsulinemia in
obese animals and humans in a way greatly independent from food intake. Objective: The …