GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus

JJ Meier - Nature Reviews Endocrinology, 2012 - nature.com
In healthy humans, the incretin glucagon-like peptide 1 (GLP-1) is secreted after eating and
lowers glucose concentrations by augmenting insulin secretion and suppressing glucagon …

Glucagon-like peptide 1 receptor agonists for type 2 diabetes

D Hinnen - Diabetes spectrum, 2017 - Am Diabetes Assoc
The incretin system has become an important target in the treatment of type 2 diabetes in
recent years, and glucagon-like peptide 1 (GLP-1) is of particular interest for its glucose …

[HTML][HTML] Overview of glucagon-like peptide-1 receptor agonists for the treatment of patients with type 2 diabetes

KL Tran, YI Park, S Pandya, NJ Muliyil… - American health & …, 2017 - ncbi.nlm.nih.gov
Background It is estimated that 29.1 million people or 9.3% of the US population have
diabetes, which contributes to considerable medical and financial burden. Type 2 diabetes …

[HTML][HTML] A clinical review of GLP-1 receptor agonists: efficacy and safety in diabetes and beyond

L Prasad-Reddy, D Isaacs - Drugs in context, 2015 - ncbi.nlm.nih.gov
The prevalence of type 2 diabetes is increasing at an astounding rate. Many of the agents
used to treat type 2 diabetes have undesirable adverse effects of hypoglycemia and weight …

[HTML][HTML] Recent updates on GLP-1 agonists: Current advancements & challenges

D Sharma, S Verma, S Vaidya, K Kalia… - Biomedicine & …, 2018 - Elsevier
Abstract Glucagon-like peptide (GLP)-1 is an incretin hormone exhibiting several
pharmacological actions such as neuroprotection, increased cognitive function, cardio …

Comparison review of short-acting and long-acting glucagon-like peptide-1 receptor agonists

A Uccellatore, S Genovese, I Dicembrini, E Mannucci… - Diabetes therapy, 2015 - Springer
Abstract Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1 RAs) are useful tools for
treating type 2 diabetes mellitus. In their recent position statement, the American Diabetes …

Efficacy and tolerability of glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes mellitus

KB Harris, DJ McCarty - Therapeutic Advances in …, 2015 - journals.sagepub.com
Glucagon-like peptide-1 (GLP-1) has been evaluated for use in the treatment of type 2
diabetes mellitus (T2DM) due to its role in glucose regulation. Four GLP-1 receptor agonists …

GLP-1 receptor agonists: a review of head-to-head clinical studies

JM Trujillo, W Nuffer, SL Ellis - Therapeutic advances in …, 2015 - journals.sagepub.com
Glucagon-like peptide-1 receptor agonists (GLP-1 RA) are attractive options for the
treatment of type 2 diabetes (T2D) because they effectively lower A1C and weight while …

User's guide to mechanism of action and clinical use of GLP-1 receptor agonists

CF Shaefer Jr, P Kushner, R Aguilar - Postgraduate Medicine, 2015 - Taylor & Francis
Abstract Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) are injectable
glucose-lowering medications approved for the treatment of adult patients with type 2 …

GLP‐1 receptor agonists for type 2 diabetes mellitus: recent developments and emerging agents

JM Trujillo, W Nuffer - Pharmacotherapy: The Journal of Human …, 2014 - Wiley Online Library
More than 26 million people in the United States have type 2 diabetes mellitus (T2D). Many
treatment options exist, but achieving long‐term glycemic control in patients with T2D …