GLP-1 receptor agonists in the treatment of type 2 diabetes: role and clinical experience to date
SA Brunton, CH Wysham - Postgraduate medicine, 2020 - Taylor & Francis
ABSTRACT Glucagon-like peptide-1 (GLP-1) is a hormone of the incretin system
responsible for a variety of glucoregulatory effects, including glucose-dependent secretion of …
responsible for a variety of glucoregulatory effects, including glucose-dependent secretion of …
Glucagon-like peptide-1 receptor agonists for the treatment of type 2 diabetes: differences and similarities
Abstract Glucagon-like peptide-1 (GLP-1) is a gastrointestinal hormone, secreted in
response to ingestion of nutrients, and has important effects on several of the …
response to ingestion of nutrients, and has important effects on several of the …
Incretin hormone mimetics and analogues in diabetes therapeutics
The incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent
insulinotropic polypeptide (GIP) are physiological gut peptides with insulin-releasing and …
insulinotropic polypeptide (GIP) are physiological gut peptides with insulin-releasing and …
GLP-1 analogs and DPP-4 inhibitors in type 2 diabetes therapy: review of head-to-head clinical trials
MP Gilbert, RE Pratley - Frontiers in endocrinology, 2020 - frontiersin.org
The incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent
insulinotropic polypeptide (GIP) are released from enteroendocrine cells in response to the …
insulinotropic polypeptide (GIP) are released from enteroendocrine cells in response to the …
A review of GLP‐1 receptor agonists in type 2 diabetes: a focus on the mechanism of action of once‐weekly agents
S Cornell - Journal of clinical pharmacy and therapeutics, 2020 - Wiley Online Library
What is known and objective Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) are
one of the preferred approved treatment options for people with type 2 diabetes (T2D) and …
one of the preferred approved treatment options for people with type 2 diabetes (T2D) and …
Incretin-based therapy: a powerful and promising weapon in the treatment of type 2 diabetes mellitus
C Koliaki, J Doupis - Diabetes Therapy, 2011 - Springer
Type 2 diabetes mellitus (T2DM) is a progressive multisystemic disease that increases
significantly cardiovascular morbidity and mortality. It is associated with obesity, insulin …
significantly cardiovascular morbidity and mortality. It is associated with obesity, insulin …
The safety and tolerability of GLP‐1 receptor agonists in the treatment of type 2 diabetes: a review
VR Aroda, R Ratner - Diabetes/metabolism research and …, 2011 - Wiley Online Library
Although several classes of pharmacotherapy are available for type 2 diabetes, glycaemic
control is often hampered by medication‐related adverse effects and contraindications such …
control is often hampered by medication‐related adverse effects and contraindications such …
GLP‐1: physiological effects and potential therapeutic applications
K Aaboe, T Krarup, S Madsbad… - Diabetes, Obesity and …, 2008 - Wiley Online Library
Glucagon‐like peptide 1 (GLP‐1) is a gut‐derived incretin hormone with the potential to
change diabetes. The physiological effects of GLP‐1 are multiple, and many seem to …
change diabetes. The physiological effects of GLP‐1 are multiple, and many seem to …
Glucagon-like peptide 1 and its derivatives in the treatment of diabetes
MA Nauck, JJ Meier - Regulatory peptides, 2005 - Elsevier
Glucagon-like peptide 1 (GLP-1) was discovered as an insulinotropic gut hormone,
suggesting a physiological role as an incretin hormone, ie, being responsible, in part, for the …
suggesting a physiological role as an incretin hormone, ie, being responsible, in part, for the …
GLP‐1 receptor agonists: Nonglycemic clinical effects in weight loss and beyond
D Ryan, A Acosta - Obesity, 2015 - Wiley Online Library
Obective Glucagon‐like peptide‐1 (GLP‐1) receptor agonists are indicated for treatment of
type 2 diabetes since they mimic the actions of native GLP‐1 on pancreatic islet cells …
type 2 diabetes since they mimic the actions of native GLP‐1 on pancreatic islet cells …