In this issue of Pediatrics, the vaccine research group at Kaiser Permanente Northern
California (KPNC) contributed another important article outlining the challenges of pertussis …

OBJECTIVE. We sought to describe the rates of pertussis hospitalization among infants by
using databases that do not rely on passive reporting and compare with results obtained …

Background: In the United States, pertussis circulation persists and primarily infects infants
and children, despite routine vaccinations. To minimize infant morbidity and mortality from …

Background. Pertussis is among the most poorly controlled bacterial vaccine-preventable
diseases in the United States. In 2006, a tetanus, reduced-dose diphtheria, and acellular …

High rates of pertussis disease in adolescents suggest that additional boosting against
pertussis would be beneficial. A combined acellular-pertussis-containing booster vaccine …

Combination vaccines consisting of multiple vaccine antigens delivered in a single injection
greatly simplify vaccine administration and are a high priority for parents, physicians and …

Background: In clinical trials, diphtheria, tetanus and acellular pertussis vaccines have been
shown to be less reactogenic than whole-cell combination vaccines. Aim: To evaluate …

To the Editor—With great interest I read the article by Slifka et al [1] who reported convincing
evidence that performing regular booster vaccinations against diphtheria and tetanus in …

OBJECTIVES: To evaluate the safety and immunogenicity of an additional birth dose of
diphtheria, tetanus, and acellular pertussis vaccine (DTaP). STUDY DESIGN: Fifty infants …

Four vaccines containing diphtheria and tetanus toxoids and acellular pertussis vaccine
(DTaP) are currently licensed in the United States for use among infants and young children …