Importance There is accumulating literature on waning acellular pertussis vaccine–induced
immunity, confirming the results of studies assessing the duration of protection of pertussis …

BACKGROUND: Combined tetanus toxoid, reduced diphtheria toxoid, and acellular
pertussis vaccine (Tdap) boosters for adolescents are a new strategy to prevent pertussis …

Background. The incidence of reported pertussis among adolescents, adults, and young
infants has increased sharply over the past decade. Combined acellular pertussis vaccines …

OBJECTIVE: Data on the effectiveness of the diphtheria–tetanus–acellular pertussis (DTaP)
vaccine in the first 4 years of life are sparse. We evaluated the vaccine effectiveness (VE) of …

Objective: To establish safety, immunogenicity, and batch stability of a reformulated whole
cell pertussis based diphtheria‐tetanus‐whole cell pertussis (DTP) vaccine (nDTPw) …

INTRODUCTION—Diphtheria is an infectious disease caused by the gram-positive bacillus
Corynebacterium diphtheriae. Infection may lead to respiratory disease, cutaneous disease …

In a multicenter, double-blind, randomized, longitudinal study, 252 children recelved
licensed Lederie diphtheria-tetanus toxoids and pertussis vaccine adsorbed (DTP) at 2, 4 …

Tetanus and diphtheria are easily preventable diseases that cause significant morbidity and
mortality in unvaccinated or inadequately immunized persons. Tetanus is caused by a …

Background: The epidemiology of pertussis is changing, with a clear increase in the number
of cases diagnosed in adolescents and adults. This development has spurred studies and …

Objective. To evaluate the safety and immunogenicity of the recombinant acellular
pertussisdiphtheria-tetanus (aPDT) vaccine (C-aPDT, Chiron/Biocine®). Study design. This …