The curative effects of some chemotherapeutic drugs are impeded by their poor permeation
through the cell membrane. This limitation can be overcome by a novel approach called …

Electroporation is a well-known phenomenon that occurs at the cell membrane when cells
are exposed to high-intensity electric pulses. Depending on electric pulse amplitude and …

Electrochemotherapy combines administration of nonpermeant or poorly permeant
chemotherapeutic drugs with application of electric pulses to the tumors in order to facilitate …

Electroporation-Based Therapies for Cancer reviews electroporation-based clinical studies
in hospitals for various cancer treatments, including melanomas, head and neck cancers …

Tissue electroporation has been explored to enhance the local delivery of
chemotherapueutic agents to solid tumors. The technique, known as electrochemotherapy …

The combined treatment consisting of a chemotherapeutic agent and pulsed electric fields
has been termed electrochemotherapy. This relatively new treatment modality relies on the …

When a cell is exposed to a sufficiently intense electric field (for a sufficient duration), local
defects in the cell membrane appear and become permeable to molecules that otherwise …

Electroporation is a standard laboratory technique originally developed for in vitro transfer of
molecules into cells. It involves application of electrical pulses ranging from micro-to …

Many conventional chemotherapeutic drugs, as well as DNA for cancer gene therapy,
require efficient access to the cells' interior to be effective. The cell membrane is a …

Electroporation uses pulsed, high‐intensity electric fields to temporarily increase cell
membrane permeability by creation of pores, through which small molecules, such as …