Advances in recent patent and clinical trial drug development for Alzheimer's disease

H Liu, L Wang, W Su, XQ Xie - Pharmaceutical patent analyst, 2014 - Taylor & Francis
Alzheimer's disease (AD) is a progressive neurodegenerative disease, involving a large
number of genes, proteins and their complex interactions. Currently, no effective therapeutic …

[HTML][HTML] Pathological mechanisms and therapeutic strategies for Alzheimer's disease

Y Ju, KY Tam - Neural regeneration research, 2022 - journals.lww.com
Alzheimer's disease is a rather complex neurodegenerative disease, which is attributed to a
combination of multiple factors. Among the many pathological pathways, synaptic …

Natural products as promising drug candidates for the treatment of Alzheimer's disease: molecular mechanism aspect

N Ansari, F Khodagholi - Current neuropharmacology, 2013 - ingentaconnect.com
Alzheimer's disease (AD) is the most common neurodegenerative disorder to date, with no
curative or preventive therapy. Histopathological hallmarks of AD include deposition of β …

[HTML][HTML] Therapeutic effects of natural drugs on Alzheimer's disease

Y Ma, M Yang, X Li, J Yue, J Chen, M Yang… - Frontiers in …, 2019 - frontiersin.org
Alzheimer disease (AD) is characterized as a chronic neurodegenerative disease
associated with aging. The clinical manifestations of AD include latent episodes of memory …

Recent developments in natural and synthetic drug research for Alzheimer's disease

G Orhan, I Orhan, B Sener - Letters in Drug Design & Discovery, 2006 - ingentaconnect.com
Alzheimer's Disease (AD) is a progressive and degenerative neurological disorder
characterized by loss of cognition and memory. However, the pathogenesis of AD is still not …

Emerging targets in neurodegeneration: new opportunities for Alzheimer's disease treatment?

A Rampa, S Gobbi, F Belluti… - Current Topics in Medicinal …, 2013 - ingentaconnect.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the brain
associated with memory impairment, progressive cognitive decline and changes in …

Nutraceuticals: An emerging therapeutic approach against the pathogenesis of Alzheimer's disease

P Sadhukhan, S Saha, S Dutta, S Mahalanobish… - Pharmacological …, 2018 - Elsevier
Alzheimer's disease (AD) is regarded as a progressive and devastating neurodegenerative
disorder. In aged individuals, it is the most prevalent cause of dementia and is characterized …

[HTML][HTML] New treatment strategies for Alzheimer's disease: is there a hope?

I Aprahamian, F Stella, OV Forlenza - Indian Journal of Medical …, 2013 - journals.lww.com
Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disease, and
corresponds to the most common cause of dementia worldwide. Although not fully …

[PDF][PDF] Pathophysiology and management of Alzheimer's disease: An overview

AK Thakur, P Kamboj, K Goswami, K Ahuja - J anal pharm Res, 2018 - researchgate.net
Alzheimer's disease (AD) is the sixth-leading reason of fatality and is 70% present in all
cases of dementia. The global burden of AD is expected to accelerate from 26.6 million …

Current drug targets for Alzheimer's disease treatment

DK Lahiri, MR Farlow, NH Greig… - Drug development …, 2002 - Wiley Online Library
Abstract Alzheimer's disease (AD), the most common form of dementia among the elderly, is
a progressive, degenerative disorder of the brain with a loss of memory and cognition. A …