Hepadnaviruses, including human hepatitis B virus (HBV), replicate through reverse
transcription of an RNA intermediate, the pregenomic RNA (pgRNA). Despite this kinship to …

Hepatitis B virus (HBV), the causative agent of B-type hepatitis in humans, is the type
member of the Hepadnaviridae, hepatotropic DNA viruses that replicate via reverse …

Hepatitis B virus (HBV), the causative agent of type B hepatitis in humans, is the prototypic
member of the hepadnaviridae, a family of small enveloped DNA‐containing viruses with …

Hepatitis B virus (HBV) is a major cause of liver disease. HBV primarily infects hepatocytes
by a still poorly understood mechanism. After an endocytotic process, the nucleocapsids are …

Chronic hepatitis B continues to be one of the most widespread and serious viral infections
in humans worldwide. Several fundamental aspects of the molecular biology of its causative …

Hepatitis B virus (HBV) is one of the smallest enveloped DNA viruses and the prototype
member of the family of Hepadnaviridae that causes acute and chronic infections of …

Although the recognition of hepatitis as an infectious disease dates to antiq uity, the
identification of hepatitis B virus (HBV) as one of its important causes was not achieved until …

Hepatitis B viruses are pararetroviruses that contain a partially dsDNA genome and replicate
this DNA through an RNA intermediate (the pregenomic RNA, pgRNA) by reverse …

This article reviews the molecular biology of the hepatitis B virus in an effort to explain its
natural history from a molecular perspective. The life cycle of the virus, with special attention …

The hepatitis B virus (HBV) particle consists of an envelope containing three related surface
proteins and probably lipid and an icosahedral nucleocapsid of approximately 30 nm …