Cell communication by tunneling nanotubes: Implications in disease and therapeutic applications

R Mittal, E Karhu, JS Wang, S Delgado… - Journal of cellular …, 2019 - Wiley Online Library
Intercellular communication is essential for the development and maintenance of
multicellular organisms. Tunneling nanotubes (TNTs) are a recently recognized means of …

Emerging physiological and pathological implications of tunneling nanotubes formation between cells

S Sisakhtnezhad, L Khosravi - European journal of cell biology, 2015 - Elsevier
Cell-to-cell communication is a critical requirement to coordinate behaviors of the cells in a
community and thereby achieve tissue homeostasis and conservation of the multicellular …

Peering into tunneling nanotubes—The path forward

D Cordero Cervantes, C Zurzolo - The EMBO journal, 2021 - embopress.org
Abstract The identification of Tunneling Nanotubes (TNTs) and TNT‐like structures signified
a critical turning point in the field of cell‐cell communication. With hypothesized roles in …

[HTML][HTML] Opportunities and challenges in tunneling nanotubes research: how far from clinical application?

X Han, X Wang - International journal of molecular sciences, 2021 - mdpi.com
Tunneling nanotubes (TNTs) are recognized long membrane nanotubes connecting
distance cells. In the last decade, growing evidence has shown that these subcellular …

Identification and characterization of tunneling nanotubes for intercellular trafficking

S Abounit, E Delage, C Zurzolo - Current protocols in cell …, 2015 - Wiley Online Library
Tunneling nanotubes (TNTs) are thin membranous channels providing direct cytoplasmic
connection between remote cells. They are commonly observed in different cell cultures and …

[HTML][HTML] Multifaceted roles of tunneling nanotubes in intercellular communication

L Marzo, K Gousset, C Zurzolo - Frontiers in physiology, 2012 - frontiersin.org
Cell-to-cell communication and exchange of materials are vital processes in multicellular
organisms during cell development, cell repair, and cell survival. In neuronal and …

[HTML][HTML] Tunneling nanotubes and gap junctions–their role in long-range intercellular communication during development, health, and disease conditions

J Ariazi, A Benowitz, V De Biasi… - Frontiers in molecular …, 2017 - frontiersin.org
Cell-to-cell communication is essential for the organization, coordination, and development
of cellular networks and multi-cellular systems. Intercellular communication is mediated by …

[HTML][HTML] Tunneling nanotubes: a new target for nanomedicine?

I Ottonelli, R Caraffi, G Tosi, MA Vandelli… - International Journal of …, 2022 - mdpi.com
Tunneling nanotubes (TNTs), discovered in 2004, are thin, long protrusions between cells
utilized for intercellular transfer and communication. These newly discovered structures …

[HTML][HTML] Tunneling nanotubes: Reshaping connectivity

C Zurzolo - Current opinion in cell biology, 2021 - Elsevier
Tunneling nanotubes (TNTs), open membranous channels between connected cells,
represent a novel direct way of communication between distant cells for the diffusion of …

[HTML][HTML] The art of cellular communication: tunneling nanotubes bridge the divide

S Gurke, JFV Barroso, HH Gerdes - Histochemistry and cell biology, 2008 - Springer
The ability of cells to receive, process, and respond to information is essential for a variety of
biological processes. This is true for the simplest single cell entity as it is for the highly …