There is enormous global anticipation for stem cell-based therapies that are safe and
effective. Numerous pre-clinical studies present encouraging results on the therapeutic …

Stem cells have the capacity for self‐renewal and capability of differentiation to various cell
lineages. Thus, they represent an important building block for regenerative medicine and …

Stem cells are the self-renewing progenitors of several body tissues and are classified
according to their origin and their ability to differentiate. Current research focuses on the …

First discovered by Friedenstein in 1976, mesenchymal stem cells (MSCs) are adult stem
cells found throughout the body that share a fixed set of characteristics. Discovered initially …

Abstract The concept of Regenerative Medicine combined with Cell based Therapy and
Tissue Engineering represents the fourth pillar of healthcare and provides a promising …

The need to search for new, alternative treatments for various diseases has prompted
scientists and physicians to focus their attention on regenerative medicine and broadly …

It has always been an ambitious goal in medicine to repair or replace morbid tissues for
regaining the organ functionality. This challenge has recently gained momentum through …

It was shown as long as half a century ago that bone marrow is a source of not only
hematopoietic stem cells, but also stem cells of mesenchymal tissues. Then the term …

Since the 1960s and the therapeutic use of hematopoietic stem cells of bone marrow origin,
there has been an increasing interest in the study of undifferentiated progenitors that have …

Abstract Background Mesenchymal stem cells (MSCs) are multipotent, genomic stable, self-
renewable, and culturally expandable adult stem cells. MSCs facilitate tissue development …