Experimental models and methods for cutaneous wound healing assessment

DS Masson‐Meyers, TAM Andrade… - International journal …, 2020 - Wiley Online Library
Wound healing studies are intricate, mainly because of the multifaceted nature of the wound
environment and the complexity of the healing process, which integrates a variety of cells …

[HTML][HTML] Research techniques made simple: animal models of wound healing

A Grada, J Mervis, V Falanga - Journal of Investigative Dermatology, 2018 - Elsevier
Animal models have been developed to study the complex cellular and biochemical
processes of wound repair and to evaluate the efficacy and safety of potential therapeutic …

Novel insights into wound healing sequence of events

L Braiman-Wiksman, I Solomonik… - Toxicologic …, 2007 - journals.sagepub.com
Effective wound healing leads to restoration of tissue integrity and occurs through a highly
organized multistage process involving various cell types. Currently, methods for wound …

Development of an in vitro burn wound model

NA Coolen, M Vlig… - Wound repair and …, 2008 - Wiley Online Library
Healing of a deeper burn wound is a complex process that often leads to scar formation.
Skin wound model systems are important for the development of treatments preventing …

Non‐animal models of wound healing in cutaneous repair: in silico, in vitro, ex vivo, and in vivo models of wounds and scars in human skin

S Ud‐Din, A Bayat - Wound Repair and Regeneration, 2017 - Wiley Online Library
Tissue repair models are essential to explore the pathogenesis of wound healing and scar
formation, identify new drug targets/biomarkers and to test new therapeutics. However, no …

Wound healing models: A systematic review of animal and non-animal models

DG Sami, HH Heiba, A Abdellatif - Wound Medicine, 2019 - Elsevier
Chronic wounds and ulcers are a significant challenge to researchers and healthcare
providers. Research into the area of wound care is in great need due to the increase in …

Models of wound healing: an emphasis on clinical studies

KP Wilhelm, D Wilhelm… - Skin Research and …, 2017 - Wiley Online Library
Background The healing of wounds has always provided challenges for the medical
community whether chronic or acute. Understanding the processes which enable wounds to …

Considerations for selecting the correct animal model for dermal wound-healing studies

WJ Lindblad - Journal of Biomaterials Science, Polymer Edition, 2008 - Taylor & Francis
An array of animal models has been described to elucidate wound-healing processes and
access the impact of various therapies on healing. However, which model to use for different …

Models for use in wound healing research: a survey focusing on in vitro and in vivo adult soft tissue

F Gottrup, MS Ågren, T Karlsmark - Wound Repair and …, 2000 - Wiley Online Library
Many different factors must be considered before selecting a wound healing model to use for
a specific study. A wide variety of models have been developed that examine different …

[HTML][HTML] In vitro wound healing assays–state of the art

A Stamm, K Reimers, S Strauß, P Vogt, T Scheper… - …, 2016 - degruyter.com
Wound healing is essential for the restoration of the barrier function of the skin. During this
process, cells at the wound edges proliferate and migrate, leading to re-epithelialization of …