Cancer vaccines have encountered their ideal personalized partner along with evidence for
great breakthroughs in the identification and synthesis of neoantigens. Individual cancer …

Cancer immunotherapy has achieved multiple clinical benefits and has become an
indispensable component of cancer treatment. Targeting tumor-specific antigens, also …

The recent success of cancer immunotherapies has highlighted the benefit of harnessing the
immune system for cancer treatment. Vaccines have a long history of promoting immunity to …

Neoantigens are tumor-specific proteins and peptides that can be highly immunogenic.
Immune-mediated tumor rejection is strongly associated with cytotoxic responses to …

Within the past decade, the field of immunotherapy has revolutionized the treatment of many
cancers with the development and regulatory approval of various immune-checkpoint …

Personal neoantigen–based cancer vaccines are designed to target antigens arising from
tumor-specific mutations within individual cancers and present a tremendous opportunity to …

During their development and progression tumors acquire numerous mutations that, when
translated into proteins give rise to neoantigens that can be recognized by T cells. Initially …

Alternatives to conventional cancer treatments are highly sought after for high-risk
malignancies that have a poor response to established treatment modalities. With research …

Immunotherapy treatments harnessing the immune system herald a new era of personalized
medicine, offering considerable benefits for cancer patients. Over the past years, tumor …

Cancer neoantigens derived from random somatic mutations in tumor tissue represent an
attractive type of targets for the cancer immunotherapies including cancer vaccine …