Berberine promotes glucose consumption independently of AMP-activated protein kinase activation
M Xu, Y Xiao, J Yin, W Hou, X Yu, L Shen, F Liu, L Wei… - Plos one, 2014 - journals.plos.org
Berberine is a plant alkaloid with anti-diabetic action. Activation of AMP-activated protein
kinase (AMPK) pathway has been proposed as mechanism for berberine's action. This study …
kinase (AMPK) pathway has been proposed as mechanism for berberine's action. This study …
Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states
YS Lee, WS Kim, KH Kim, MJ Yoon, HJ Cho, Y Shen… - Diabetes, 2006 - Am Diabetes Assoc
Berberine has been shown to have antidiabetic properties, although its mode of action is not
known. Here, we have investigated the metabolic effects of berberine in two animal models …
known. Here, we have investigated the metabolic effects of berberine in two animal models …
Sodium caprate augments the hypoglycemic effect of berberine via AMPK in inhibiting hepatic gluconeogenesis
Berberine (BER), a natural product and active ingredient of genera Berberis and Coptis, has
been demonstrated to possess anti-diabetic activities. However, the poor bioavailability of …
been demonstrated to possess anti-diabetic activities. However, the poor bioavailability of …
[HTML][HTML] Berberine improves glucose metabolism through induction of glycolysis
J Yin, Z Gao, D Liu, Z Liu, J Ye - American Journal of …, 2008 - journals.physiology.org
Berberine, a botanical alkaloid used to control blood glucose in type 2 diabetes in China,
has recently been reported to activate AMPK. However, it is not clear how AMPK is activated …
has recently been reported to activate AMPK. However, it is not clear how AMPK is activated …
Berberine improves glucose and lipid metabolism in HepG2 cells through AMPKα1 activation
G Ren, JH Guo, YZ Qian, WJ Kong… - Frontiers in …, 2020 - frontiersin.org
Aim This study is designed to investigate whether or not AMP-activated protein kinase α1
(AMPKα1) is required for natural product berberine (BBR) to improve glucose and lipid …
(AMPKα1) is required for natural product berberine (BBR) to improve glucose and lipid …
Berberine acutely inhibits insulin secretion from β-cells through 3′, 5′-cyclic adenosine 5′-monophosphate signaling pathway
L Zhou, X Wang, L Shao, Y Yang, W Shang… - …, 2008 - academic.oup.com
Berberine, a hypoglycemic agent, has recently been shown to activate AMP-activated
protein kinase (AMPK) contributing to its beneficial metabolic effects in peripheral tissues …
protein kinase (AMPK) contributing to its beneficial metabolic effects in peripheral tissues …
Berberine inhibits mouse insulin gene promoter through activation of AMP activated protein kinase and may exert beneficial effect on pancreatic β-cell
N Shen, Y Huan, Z Shen - European Journal of Pharmacology, 2012 - Elsevier
Berberine is one of the main alkaloids of Rhizoma coptidis, proven to have anti-diabetic
potentials through activation of AMP activated protein kinase (AMPK) in liver and muscle …
potentials through activation of AMP activated protein kinase (AMPK) in liver and muscle …
[HTML][HTML] Effects and mechanisms of berberine in diabetes treatment
J Yin, J Ye, W Jia - Acta Pharmaceutica Sinica B, 2012 - Elsevier
Abstract Berberine from Rhizoma Coptidis is an oral hypoglycemic agent with anti-
dyslipidemia and anti-obesity activities. Its metabolic activity of regulating blood glucose and …
dyslipidemia and anti-obesity activities. Its metabolic activity of regulating blood glucose and …
Berberine-induced activation of 5′-adenosine monophosphate–activated protein kinase and glucose transport in rat skeletal muscles
X Ma, T Egawa, H Kimura, K Karaike, S Masuda… - Metabolism, 2010 - Elsevier
Berberine (BBR) is the main alkaloid of Coptis chinensis, which has been used as a folk
medicine to treat diabetes mellitus in Asian countries. We explored the possibility that 5 …
medicine to treat diabetes mellitus in Asian countries. We explored the possibility that 5 …
Berberine inhibits glucose oxidation and insulin secretion in rat islets
M Bai, Y Liu, F Zhou, Y Zhang, Q Zhu, L Zhang… - Endocrine …, 2018 - jstage.jst.go.jp
Glucose promotes insulin secretion primarily via its metabolism and the production of
metabolic coupling factors in beta-cells. The activation of AMP-activated protein kinase …
metabolic coupling factors in beta-cells. The activation of AMP-activated protein kinase …