miR-152-3p aggravates vascular endothelial cell dysfunction by targeting DEAD-box helicase 6 (DDX6) under hypoxia

Z Zhao, C Wu, X He, E Zhao, S Hu, Y Han, T Wang… - …, 2021 - Taylor & Francis
Stroke is a main cause of disability and death worldwide, and ischemic stroke accounts for
most stroke cases. Recently, microRNAs (miRNAs) have been verified to play critical roles in …

MicroRNA let-7f alleviates vascular endothelial cell dysfunction via targeting HMGA2 under oxygen-glucose deprivation and reoxygenation

Z Zhao, C Wu, X He, E Zhao, S Hu, Y Han, T Wang… - Brain research, 2021 - Elsevier
Stroke is a fatal disease with high disability and mortality and there is no credible treatment
for stroke at present. Studies on stroke are extensively developed to explore the underlying …

Hypoxia-Induced miR-101 Impairs Endothelial Barrier Integrity Through Altering VE-Cadherin and Claudin-5

A Shukla, U Bhardwaj, Apoorva, P Seth… - Molecular …, 2024 - Springer
Stroke is a life-threatening medical condition across the world that adversely affects the
integrity of the blood–brain barrier (BBB). The brain microvascular endothelial cells are the …

[HTML][HTML] MiR-202-5p attenuates neurological deficits and neuronal injury in MCAO model rats and OGD-induced injury in Neuro‐2a cells by targeting eIF4E-mediated …

B Li, Z Huang, J Meng, W Yu, H Yang - Molecular and cellular probes, 2020 - Elsevier
Ischemic stroke is a common cerebrovascular disease caused by insufficient blood supply to
the brain. In recent years, studies have demonstrated that microRNAs (miRNAs) are …

Let-7i attenuates human brain microvascular endothelial cell damage in oxygen glucose deprivation model by decreasing toll-like receptor 4 expression

W Xiang, C Tian, S Peng, L Zhou, S Pan… - … and biophysical research …, 2017 - Elsevier
The let-7 family of microRNAs (miRNAs) plays an important role on endothelial cell function.
However, there have been few studies on their role under ischemic conditions. In this study …

Down-Regulation of miRNA-1303 Promotes the Angiogenesis of HUVECs via Targeting THSD7A

G Xiang, Y Zhao, D Jin, Y Fang, Z Li, X He, Y Zhai… - Molecular …, 2023 - Springer
Angiogenesis promotes neurological recovery after acute ischemic stroke (AIS), and
microRNAs play crucial roles in cerebral angiogenesis. This study found that Homo sapiens …

Upregulation of miR-219a-5p decreases cerebral ischemia/reperfusion injury in vitro by targeting Pde4d

MY Lu, JR Wu, RB Liang, YP Wang, YC Zhu… - Journal of Stroke and …, 2020 - Elsevier
Background: Ischemic stroke is the leading cause of disability and death globally. Micro-
RNAs (miRNAs) have been reported to play important roles in the development and …

Downregulation of miRNA-134 protects neural cells against ischemic injury in N2A cells and mouse brain with ischemic stroke by targeting HSPA12B

W Chi, F Meng, Y Li, Q Wang, G Wang, S Han, P Wang… - Neuroscience, 2014 - Elsevier
MicroRNAs (miRNAs) have emerged as a major regulator in neurological diseases, and
understanding their molecular mechanism in modulating cerebral ischemic injury may …

MicroRNA-126-5p facilitates hypoxia-induced vascular endothelial cell injury via HIPK2

Y Liao, Y Zou, H Zhang - Annals of Clinical & Laboratory …, 2022 - Assoc Clin Scientists
Objective We intended to study the specific function of microRNA-126-5p (miR-126-5p) in
myocardial infarction (MI) and its underlying mechanisms of action in hypoxia-treated human …

[HTML][HTML] MiR-140–3p directly targets Tyro3 to regulate OGD/R-induced neuronal injury through the PI3K/Akt pathway

Y Zhang, Q Su, W Xia, K Jia, D Meng, X Wang, X Ni… - Brain Research …, 2023 - Elsevier
Background and purpose MicroRNAs (miRNAs) are highly expressed in the central nervous
system and play important roles in ischaemic stroke pathogenesis. However, the role of …