Kv4 channels mediate most of the somatodendritic subthreshold operating A‐type current
(ISA) in neurons. This current plays essential roles in the regulation of spike timing, repetitive …

The subthreshold‐operating A‐type K+ current in neurons (ISA) has important roles in the
regulation of neuronal excitability, the timing of action potential firing and synaptic …

Dipeptidyl peptidase-like protein 6 (DPP6) proteins co-assemble with Kv4 channel α-
subunits and Kv channel-interacting proteins (KChIPs) to form channel protein complexes …

The channels mediating most of the somatodendritic A-type K+ current in neurons are
thought to be ternary complexes of Kv4 pore-forming subunits and two types of auxiliary …

In the nervous system, a wide diversity of K+ channels are formed by the oligomeric
assembly of subunits encoded by a large number of K+ channel genes. The physiological …

Serôdio, Paulo and Bernardo Rudy. Differential expression of Kv4 K+ channel subunits
mediating subthreshold transient K+ (A-type) currents in rat brain. J. Neurophysiol. 79: 1081 …

Kv4 pore‐forming subunits are the principal constituents of the voltage‐gated K+ channel
underlying somatodendritic subthreshold A‐type currents (ISA) in neurones. Two structurally …

Key points• A‐type K+ currents, IA, are key determinants of neuronal excitability. Previous
studies suggest critical roles for voltage‐gated K+ (Kv) channel pore‐forming (α) subunits of …

In cerebellar Purkinje cells, Kv3 potassium channels are indispensable for firing at high
frequencies. In Purkinje cells from young mice (P4–P7), Kv3 currents, recorded in whole-cell …

A-type K+ currents have unique kinetic and voltage-dependent properties that allow them to
finely tune synaptic integration, action potential (AP) shape and firing patterns. In …