The cytokine network in heart failure: pathogenetic importance and potential therapeutic targets.

L Gullestad, P Aukrust - Heart Failure Monitor, 2001 - europepmc.org
Accumulating evidence indicates that inflammatory mediators are important in the
pathogenesis of chronic heart failure. Several studies have shown raised levels of …

Inflammatory cytokines in heart failure: mediators and markers

L Gullestad, T Ueland, LE Vinge, A Finsen, A Yndestad… - Cardiology, 2012 - karger.com
Evidence from both experimental and clinical trials indicates that inflammatory mediators are
of importance in the pathogenesis of chronic heart failure (HF) contributing to cardiac …

Role of inflammation in the progression of heart failure

A Yndestad, JK Damås, E Øie, T Ueland… - Current cardiology …, 2007 - Springer
Chronic heart failure (HF) is a disorder characterized in part by immune activation and
inflammation. Thus, patients with HF have elevated levels of a number of inflammatory …

Inflammatory and anti‐inflammatory cytokines in chronic heart failure: potential therapeutic implications

P Aukrust, L Gullestad, T Ueland, JK Damås… - Annals of …, 2005 - Taylor & Francis
Persistent inflammation, involving increased levels of inflammatory cytokines, seems to play
a pathogenic role in chronic heart failure (HF) by influencing heart contractility, inducing …

[HTML][HTML] Cytokines as new treatment targets in chronic heart failure

JK Damås, L Gullestad, P Aukrust - Trials, 2001 - Springer
Inflammatory cytokines may negatively influence contractility and contribute to the
remodelling process in the failing myocardium. Traditional cardiovascular drugs appear to …

Therapeutic potential of anticytokine therapy in congestive heart failure

P Aukrust, A Yndestad, JK Damås… - American Journal of …, 2004 - Springer
Accumulating evidence indicates that inflammatory cytokines play a pathogenic role in
congestive heart failure (CHF) by influencing heart contractility, inducing hypertrophy, and …

A glossary of circulating cytokines in chronic heart failure

S Adamopoulos, JT Parissis… - European journal of …, 2001 - Wiley Online Library
Recent studies have emphasized the importance of biologically active molecules, termed
cytokines, in the development and progression of the syndrome of chronic heart failure. This …

Review of trials in chronic heart failure showing broad-spectrum anti-inflammatory approaches

L Gullestad, P Aukrust - The American journal of cardiology, 2005 - Elsevier
Accumulating evidence indicates that inflammatory mediators are important in the
pathogenesis of chronic heart failure (CHF), contributing to cardiac remodeling and …

Immune modulation: role of the inflammatory cytokine cascade in the failing human heart

M Satoh, Y Minami, Y Takahashi… - Current heart failure reports, 2008 - Springer
Recent studies have determined that expression of inflammatory mediators, such as
cytokines and chemokines, is an important factor in the development and progression of …

Cytokine network in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy

P Aukrust, T Ueland, E Lien, K Bendtzen… - The American journal of …, 1999 - Elsevier
Inflammatory cytokines may play a pathogenic role in the development of congestive heart
failure (CHF). Elevated circulating levels of inflammatory cytokines have been reported in …