Rare and complex mutations of epidermal growth factor receptor, and efficacy of tyrosine kinase inhibitor in patients with non-small cell lung cancer
Background There are many complex and rare mutations in the epidermal growth factor
receptor (EGFR) gene in non-small cell lung cancer (NSCLC) other than the two classical …
receptor (EGFR) gene in non-small cell lung cancer (NSCLC) other than the two classical …
Effectiveness of tyrosine kinase inhibitors on “uncommon” epidermal growth factor receptor mutations of unknown clinical significance in non–small cell lung cancer
Purpose: Clinical features of epidermal growth factor receptor (EGFR) mutations, L858R,
deletions in exon 19, T790M, and insertions in exon 20, in non–small cell lung cancer …
deletions in exon 19, T790M, and insertions in exon 20, in non–small cell lung cancer …
[HTML][HTML] Complex mutations in the epidermal growth factor receptor gene in non-small cell lung cancer
A Hata, H Yoshioka, S Fujita, K Kunimasa, R Kaji… - Journal of Thoracic …, 2010 - Elsevier
Introduction: Mutation of the epidermal growth factor receptor (EGFR) gene can predict the
efficacy of EGFR-tyrosine kinase inhibitors. Different mutations have been shown to co-occur …
efficacy of EGFR-tyrosine kinase inhibitors. Different mutations have been shown to co-occur …
[HTML][HTML] Activity of epidermal growth factor receptor-tyrosine kinase inhibitors in patients with non-small cell lung cancer harboring rare epidermal growth factor …
T De Pas, F Toffalorio, M Manzotti, C Fumagalli… - Journal of Thoracic …, 2011 - Elsevier
Introduction Mutations of the epidermal growth factor receptor (EGFR) have been proven to
predict activity of the EGFR-tyrosine kinase inhibitors (EGFR-TKI), gefitinib and erlotinib …
predict activity of the EGFR-tyrosine kinase inhibitors (EGFR-TKI), gefitinib and erlotinib …
Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non–small cell lung cancer patients treated with gefitinib or …
DM Jackman, BY Yeap, LV Sequist, N Lindeman… - Clinical Cancer …, 2006 - AACR
Purpose: Somatic mutations in the epidermal growth factor receptor (EGFR) have been
detected in patients with non–small cell lung cancer (NSCLC) and are associated with …
detected in patients with non–small cell lung cancer (NSCLC) and are associated with …
[HTML][HTML] Clinical characteristics and response to tyrosine kinase inhibitors of patients with non-small cell lung cancer harboring uncommon epidermal growth factor …
Y Zhang, Z Wang, X Hao, X Hu, H Wang… - Chinese Journal of …, 2017 - ncbi.nlm.nih.gov
Objective To investigate the clinical features of patients with non-small cell lung cancer
(NSCLC) harboring uncommon epidermal growth factor receptor (EGFR) mutations, and the …
(NSCLC) harboring uncommon epidermal growth factor receptor (EGFR) mutations, and the …
Double mutation and gene copy number of EGFR in gefitinib refractory non-small-cell lung cancer
M Tokumo, S Toyooka, S Ichihara, K Ohashi… - Lung cancer, 2006 - Elsevier
Mutations of the epidermal growth factor receptor (EGFR) gene have been reported in non-
small-cell lung cancer (NSCLC), especially in patients with adenocarcinoma and never …
small-cell lung cancer (NSCLC), especially in patients with adenocarcinoma and never …
Effectiveness of tyrosine kinase inhibitors in Japanese patients with non-small cell lung cancer harboring minor epidermal growth factor receptor mutations: results …
T Otsuka, M Mori, Y Yano, J Uchida… - Anticancer …, 2015 - ar.iiarjournals.org
Aim: Non-small cell lung cancer (NSCLC) with minor mutations in the epidermal growth
factor receptor (EGFR) gene, except for the common 15 base-pair deletions in exon 19 and …
factor receptor (EGFR) gene, except for the common 15 base-pair deletions in exon 19 and …
Clinical course of patients with non–small cell lung cancer and epidermal growth factor receptor exon 19 and exon 21 mutations treated with gefitinib or erlotinib
Purpose: In patients with non–small cell lung cancer (NSCLC), mutations in the epidermal
growth factor receptor (EGFR) tyrosine kinase domain have been associated with sensitivity …
growth factor receptor (EGFR) tyrosine kinase domain have been associated with sensitivity …
Good Response to Gefitinib in Lung Adenocarcinoma of Complex Epidermal Growth Factor Receptor (EGFR) Mutations with the Classical Mutation Pattern
SG Wu, YL Chang, YC Hsu, JY Wu, CH Yang… - The …, 2008 - academic.oup.com
Background. Epidermal growth factor receptor (EGFR) mutations are usually detected in
lung adenocarcinoma and are associated with a response to EGFR tyrosine kinase …
lung adenocarcinoma and are associated with a response to EGFR tyrosine kinase …
相关搜索
- growth factor receptor mutations
- kinase inhibitors receptor mutations
- growth factor kinase inhibitors
- lung adenocarcinoma egfr mutations
- clinical characteristics receptor mutations
- gene copy number lung cancer
- growth factor clinical characteristics
- kinase inhibitors receptor tyrosine
- growth factor receptor tyrosine
- lung adenocarcinoma mutation pattern