Maintaining organ viability between donation and transplantation is of critical importance for
optimal graft function and survival. To date in pancreas transplantation, static cold storage …

Static cold storage (SCS) is the standard method for pancreas preservation prior to
transplantation; however, it does not permit organ assessment. Normothermic reperfusion …

Background Hypothermic machine perfusion (HMP) is increasingly being used for extended
criteria kidney grafts. Pancreatic HMP is challenging because physiologically the pancreas …

Abstract Purpose of Review Pancreas transplantation enables complete patient
independence from exogenous insulin administration and increases both patient survival …

The concept of organ preservation by perfusion dates back to the mid-19th century.
Innovations since then have included temperature regulation, perfusion fluid composition …

Pancreas transplantation (PTx) is a curative treatment for people who live with the burden of
a diagnosis of diabetes mellitus (DM). However, due to organ shortages and increasing …

Introduction: Pancreas transplantation is currently one of the best treatments proposed in
highly selected patients with unstable and brittle type 1 diabetes. The objective of pancreas …

Despite a critical shortage of viable donor livers for transplantation, only a fraction of the
available organs are used. Donor organ defects, which in the majority of cases are caused …

Background Transplantation of beta cells by pancreas or islet transplantation is the
treatment of choice for a selected group of patients suffering from type 1 diabetes mellitus …

Solid organ transplant constitutes the definitive treatment for end-stage organ failure. Better
organ preservation methods have enabled use of marginal grafts, thereby expanding the …