DNA is one of the prime molecules, and its stability is of utmost importance for proper
functioning and existence of all living systems. Genotoxic chemicals and radiations exert …

Increases in ultraviolet radiation at the Earth's surface due to the depletion of the
stratospheric ozone layer have recently fuelled interest in the mechanisms of various effects …

On UV irradiation of Escherichia coli cells, DNA replication is transiently arrested to allow
removal of DNA damage by DNA repair mechanisms. This is followed by a resumption of …

Since its discovery in bacteria 25 years ago, DNA repair, particularly in response to damage
induced by UV radiation, has been a major focus of molecular biology. The roles played by …

Ultraviolet light (UV) is thought to have had a major impact on the early evolution of life. UV
is absorbed by nucleic acids and produces several types of DNA damage, which interfere …

Background Genomic instability is characteristic of many types of human cancer. Recently,
we reported that ultraviolet radiation induced elevated mutation rates and chromosomal …

Solar ultraviolet (UV) radiation generates bulky photodimers at di-pyrimidine sites that pose
stress to cells and organisms by hindering DNA replication and transcription. In addition …

Ultraviolet (UV) light is a natural genotoxic agent leading to the formation of photolesions
endangering the genomic integrity and thereby the survival of living organisms. To prevent …

DNA damage profiles have been established in plasmid DNA using purified DNA repair
enzymes and a plasmid relaxation assay, following exposure to UVC, UVB, UVA or …

Being sessile, plants are continuously exposed to DNA‐damaging agents present in the
environment such as ultraviolet (UV) and ionizing radiations (IR). Sunlight acts as an energy …