DAMP-sensing receptors in sterile inflammation and inflammatory diseases

T Gong, L Liu, W Jiang, R Zhou - Nature Reviews Immunology, 2020 - nature.com
The innate immune system has the capacity to detect 'non-self'molecules derived from
pathogens, known as pathogen-associated molecular patterns, via pattern recognition …

DAMPs and DAMP-sensing receptors in inflammation and diseases

M Ma, W Jiang, R Zhou - Immunity, 2024 - cell.com
Damage-associated molecular patterns (DAMPs) are endogenous danger molecules
produced in cellular damage or stress, and they can activate the innate immune system …

DAMPs from cell death to new life

E Vénéreau, C Ceriotti, ME Bianchi - Frontiers in immunology, 2015 - frontiersin.org
Our body handles tissue damage by activating the immune system in response to
intracellular molecules released by injured tissues [damage-associated molecular patterns …

DAMPs activating innate immune responses in sepsis

JW Kang, SJ Kim, HI Cho, SM Lee - Ageing research reviews, 2015 - Elsevier
Sepsis refers to the deleterious and non-resolving systemic inflammatory response of the
host to microbial infection and is the leading cause of death in intensive care units. The …

Complexity of danger: the diverse nature of damage-associated molecular patterns

L Schaefer - Journal of Biological Chemistry, 2014 - ASBMB
In reply to internal or external danger stimuli, the body orchestrates an inflammatory
response. The endogenous triggers of this process are the damage-associated molecular …

Extracellular DAMPs in plants and mammals: immunity, tissue damage and repair

G De Lorenzo, S Ferrari, F Cervone, E Okun - Trends in immunology, 2018 - cell.com
Innate immune receptors, well known mediators of response to non-self-molecules and
inflammation, also act as mediators of immunity triggered by 'damage-associated molecular …

Role of extracellular damage-associated molecular pattern molecules (DAMPs) as mediators of persistent pain

J Kato, CI Svensson - Progress in Molecular Biology and Translational …, 2015 - Elsevier
Damage-associated molecular pattern molecules (DAMPs) are endogenous molecules that
are constitutively expressed and released upon tissue damage, resulting in activation of the …

Damage-associated molecular patterns in cancer: a double-edged sword

C Hernandez, P Huebener, RF Schwabe - Oncogene, 2016 - nature.com
Damage-associated molecular patterns (DAMPs) are released in response to cell death and
stress, and are potent triggers of sterile inflammation. Recent evidence suggests that DAMPs …

Damage-associated molecular patterns and the systemic immune consequences of severe thermal injury

PB Comish, D Carlson, R Kang… - The journal of immunology, 2020 - journals.aai.org
Thermal injury is often associated with a proinflammatory state resulting in serious
complications. After a burn, the innate immune system is activated with subsequent immune …

Damage associated molecular pattern molecules

MT Lotze, A Deisseroth, A Rubartelli - Clinical immunology, 2007 - Elsevier
Members of the Federation of Clinical Immunology Societies are invited to attend an exciting
meeting on damage-associated molecular pattern molecules [DAMPs] in acute and chronic …