Methods Human AD-MSCs were administered intravenously on day 3, 6 and 9 after an intra-
tracheal challenge with bleomycin, whereas, pirfenidone was given orally in drinking water …

Abstract Background Mesenchymal stromal cells (MSCs) are a potential therapeutic tool for
pulmonary fibrosis. However, ex vivo MSC expansion using serum poses risks of harmful …

Pulmonary fibrosis (PF) is a chronic, progressive, fibrotic interstitial disease of the lung with
poor prognosis and without effective treatment currently. Data from previous coronavirus …

The immunogenic collagen V (Col V) and the proinflammatory cytokine interleukin (IL)-17
have been implicated in the pathogenesis of multiple autoimmune diseases. Col V is also up …

Adipose stem cells (ASCs) are detectable in the parenchyma and large airways of lungs
after systemic administration, and ameliorate inflammatory infiltration and cell death in …

Background: Lung fibrosis is considered as an end stage for many lung diseases including
lung inflammatory disease, autoimmune diseases and malignancy. There are limited …

Adipose-derived stem cells (AdSCs) have recently been considered a useful treatment tool
for autoimmune disease because of their anti-inflammatory and immunosuppressive effects …

Paracrine factors are currently considered to be the major mechanism through which
mesenchymal stem cells (MSCs) exert their actions. The aim of this study was to investigate …

Introduction Idiopathic pulmonary fibrosis is a progressive diffuse parenchymal lung disorder
of unknown etiology. Mesenchymal stem cell (MSC)-based therapy is a novel approach with …

The study was aimed to investigate the mechanism and administration timing of bone
marrow‐derived mesenchymal stem cells (BMSCs) in bleomycin (BLM)‐induced pulmonary …