The role of monocytes in the development of Tuberculosis-associated Immune Reconstitution Inflammatory Syndrome

HTT Tran, R Van den Bergh, TN Vu, K Laukens… - Immunobiology, 2014 - Elsevier
Abstract Background Tuberculosis-associated Immune Reconstitution Inflammatory
Syndrome (TB-IRIS) is a common complication of combined antiretroviral therapy (cART) in …

Modulation of the complement system in monocytes contributes to tuberculosis-associated immune reconstitution inflammatory syndrome

HTT Tran, R Van den Bergh, MM Loembé, W Worodria… - Aids, 2013 - journals.lww.com
Objective: Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS)
is a common complication in HIV-TB co-infected patients receiving combined antiretroviral …

The immunopathogenesis of the HIV tuberculosis immune reconstitution inflammatory syndrome

RPJ Lai, JK Nakiwala, G Meintjes… - European journal of …, 2013 - Wiley Online Library
HIV‐1 patients co‐infected with some pathogens are at risk of developing the immune
reconstitution inflammatory syndrome (IRIS) when initiating antiretroviral therapy (ART). IRIS …

[HTML][HTML] HIV–tuberculosis-associated immune reconstitution inflammatory syndrome is characterized by Toll-like receptor and inflammasome signalling

RPJ Lai, G Meintjes, KA Wilkinson, CM Graham… - Nature …, 2015 - nature.com
Patients with HIV-associated tuberculosis (TB) initiating antiretroviral therapy (ART) may
develop immune reconstitution inflammatory syndrome (TB-IRIS). No biomarkers for TB-IRIS …

[HTML][HTML] Lower pre-treatment T cell activation in early-and late-onset tuberculosis-associated immune reconstitution inflammatory syndrome

O Goovaerts, W Jennes, M Massinga-Loembé… - PloS one, 2015 - journals.plos.org
Background Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-
IRIS) is an inflammatory complication in HIV-TB co-infected patients receiving antiretroviral …

[HTML][HTML] Dynamics of T-lymphocyte activation related to paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome in persons with advanced …

R Tibúrcio, B Barreto-Duarte, G Naredren… - Frontiers in …, 2021 - frontiersin.org
Most persons living with HIV (PLWH) experience a significant restoration of their immunity
associated with successful inhibition of viral replication after antiretroviral therapy (ART) …

[HTML][HTML] Cytotoxic mediators in paradoxical HIV–tuberculosis immune reconstitution inflammatory syndrome

KA Wilkinson, NF Walker, G Meintjes… - The Journal of …, 2015 - journals.aai.org
Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) frequently
complicates combined antiretroviral therapy and antituberculosis therapy in HIV-1 …

Biomarkers of CD4+ T-cell activation as risk factors for tuberculosis-associated immune reconstitution inflammatory syndrome

LA Chakrabarti, C Boucherie, F Bugault, MC Cumont… - Aids, 2014 - journals.lww.com
Objective: Patients coinfected with HIV and Mycobacterium tuberculosis frequently
experience a paradoxical worsening of tuberculosis (TB) symptoms early after the initiation …

[HTML][HTML] Mycobacterial Antigen Driven Activation of CD14++CD16 Monocytes Is a Predictor of Tuberculosis-Associated Immune Reconstitution Inflammatory …

BB Andrade, A Singh, G Narendran… - PLoS …, 2014 - journals.plos.org
Paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-
IRIS) is an aberrant inflammatory response occurring in a subset of TB-HIV co-infected …

[HTML][HTML] LPS-binding protein and IL-6 mark paradoxical tuberculosis immune reconstitution inflammatory syndrome in HIV patients

O Goovaerts, W Jennes, M Massinga-Loembé… - PloS one, 2013 - journals.plos.org
Background Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-
IRIS) remains a poorly understood complication in HIV-TB co-infected patients initiating …