Zinc finger and interferon-stimulated genes play a vital role in TB-IRIS following HAART in AIDS

J Ma, F Zhao, W Su, Q Li, J Li, J Ji, Y Deng… - Personalized …, 2018 - Taylor & Francis
Aim: Co-infection in HIV-1 patients with Mycobacterium tuberculosis poses considerable risk
of developing the immune reconstitution inflammatory syndrome (IRIS), especially upon the …

Tuberculosis-associated immune reconstitution inflammatory syndrome—an extempore game of misfiring with defense arsenals

R Vignesh, P Balakrishnan, HY Tan, YK Yong, V Velu… - Pathogens, 2023 - mdpi.com
The lethal combination involving TB and HIV, known as “syndemic” diseases, synergistically
act upon one another to magnify the disease burden. Individuals on anti-retroviral therapy …

Tuberculosis-immune reconstitution inflammatory syndrome in HIV: from pathogenesis to prediction

N Gopalan, BB Andrade… - Expert review of clinical …, 2014 - Taylor & Francis
Tuberculosis-immune reconstitution inflammatory syndrome (TB-IRIS) is an exaggerated,
dysregulated immune response against dead or viable antigens of Mycobacterium …

TB-IRIS after initiation of antiretroviral therapy is associated with expansion of preexistent Th1 responses against Mycobacterium tuberculosis antigens

R Vignesh, N Kumarasamy, A Lim… - JAIDS Journal of …, 2013 - journals.lww.com
Background: The role of T-cell responses against Mycobacterium tuberculosis antigens in
tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is unclear …

Risk factors and frequency of tuberculosis-associated immune reconstitution inflammatory syndrome among HIV/Tuberculosis co-infected patients in Southern India

R Vignesh, CR Swathirajan, SS Solomon… - Indian Journal of …, 2017 - Elsevier
Immune reconstitution inflammatory syndrome (IRIS) continues to be a complication in
HIV/tuberculosis (TB) co-infected patients initiating highly active antiretroviral therapy …

[HTML][HTML] Characteristics of paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome and its influence on tuberculosis treatment outcomes in …

G Narendran, K Jyotheeswaran, T Senguttuvan… - International Journal of …, 2020 - Elsevier
Objective The influence of tuberculosis (TB)-immune reconstitution inflammatory syndrome
(IRIS) on TB treatment outcomes and its risk factors were investigated among people with …

Immunological profiling of tuberculosis-associated immune reconstitution inflammatory syndrome and non-immune reconstitution inflammatory syndrome death in HIV …

S Ravimohan, N Tamuhla, AP Steenhoff… - The Lancet Infectious …, 2015 - thelancet.com
Background Patients co-infected with advanced HIV and tuberculosis are at risk of
tuberculosis-associated immune reconstitution inflammatory syndrome (IRIS) and death …

The tuberculosis-associated immune reconstitution inflammatory syndrome: recent advances in clinical and pathogenesis research

NF Walker, C Stek, S Wasserman… - Current Opinion in …, 2018 - journals.lww.com
Specific biomarkers would aid in identifying high-risk patients for interventions and a
diagnostic test is needed. Clinicians should consider prednisone for TB-IRIS prevention in …

Corticosteroid-modulated immune activation in the tuberculosis immune reconstitution inflammatory syndrome

G Meintjes, KH Skolimowska, KA Wilkinson… - American journal of …, 2012 - atsjournals.org
Rationale: HIV–tuberculosis-associated immune reconstitution inflammatory syndrome (TB-
IRIS) is an immunopathological reaction to mycobacterial antigens induced by antiretroviral …

Hypercytokinaemia accompanies HIV–tuberculosis immune reconstitution inflammatory syndrome

R Tadokera, G Meintjes… - European …, 2011 - Eur Respiratory Soc
Increased access to combination antiretroviral therapy in areas co-endemic for tuberculosis
(TB) and HIV-1 infection is associated with an increased incidence of immune reconstitution …