Stereoselective Synthesis of (5′S)‐5′‐C‐(5‐Bromo‐2‐penten‐1‐yl)‐2′‐deoxyribofuranosyl Thymine, a New Convertible Nucleoside

V Banuls, JM Escudier, C Zedde… - European Journal of …, 2001 - Wiley Online Library
A stereoselective synthesis of (5′ S)‐5′‐C‐(5‐bromo‐2‐penten‐1‐yl)‐2′‐
deoxyribofuranosyl thymine phosphoramidite is described; the absolute stereochemistry of …

Novel nucleoside analogues with fluorophores replacing the DNA base

C Strässler, NE Davis, ET Kool - Helvetica chimica acta, 1999 - Wiley Online Library
We describe the preparation and fluorescence properties of a set of new nucleosides in
which a known hydrocarbon or oligothiophene fluorophore replaces the DNA base at C (1) …

Synthesis and incorporation of an α-hexofuranosyl thymidine into oligodeoxynucleotides via its two exocyclic OH-groups

VV Filichev, EB Pedersen - Bioorganic & medicinal chemistry letters, 2004 - Elsevier
1-(2, 3-Dideoxy-3-amino-α-d-arabino-hexofuranosyl) thymine is considered as a
conformationally restricted acyclic nucleoside using the furanose ring to link the diol …

Synthesis and hybridization properties of β-and α-oligodeoxynucleotides containing β-and α-1-(3-C-allyl-2-deoxy-D-erythro-pentofuranosyl) thymine and α-1-[3-C-(3 …

PN Jørgensen, US Sørensen, HM Pfundheller… - Journal of the …, 1997 - pubs.rsc.org
Convergent synthesis of β-and α-1-(3-C-allyl-2-deoxy-D-erythro-pentofuranosyl) thymine
and their incorporation into β-and α-oligodeoxynucleotides (ODNs) is described. The …

Post-synthetic functionalization of oligodeoxyribonucleotides at the 2′-position

H Ozaki, S Momiyama, K Yokotsuka, H Sawai - Tetrahedron Letters, 2001 - Elsevier
Post-synthetic functionalization of oligodeoxyribonucleotides at the 2′-position - ScienceDirect Skip
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Oligonucleotides containing a new type of acyclic, achiral nucleoside analogue: 1-[3-hydroxy-2-(hydroxymethyl) prop-1-enyl] thymine

T Boesen, DS Pedersen, BM Nielsen… - Bioorganic & medicinal …, 2003 - Elsevier
An achiral, acyclic nucleoside analogue has been incorporated once or twice in
oligodeoxyribonucleotides by the phosphoramidite method, and conditions found which …

A convenient synthesis of 5-hydroxy-2′-deoxycytidine phosphoramidite and its incorporation into oligonucleotides

A Romieu, D Gasparutto, D Molko, J Cadet - Tetrahedron letters, 1997 - Elsevier
Oligonucleotides containing 5-hydroxy-2′-deoxycytidine (2) have been synthesized using
the phosphoramidite chemistry. The presence and the integrity of the modified nucleoside in …

[PDF][PDF] Synthesis of diastereomeric mixtures of 5'-C-hydroxymethylthymidine and introduction of a novel class of C-hydroxymethyl functionalised oligodeoxynucleotides

J Fensholdt, J Wengel - Acta Chemica Scandinavica, 1996 - actachemscand.org
Novel 5'-C-hydroxymethyl substituted derivatives of thymidine have been prepared by
dihydroxylation of the 5'-C-methylene nucleoside 1. Osmium tetraoxide catalysed …

An inverse approach in oligodeoxyribonucleotide synthesis

T Wagner, W Pfleiderer - Nucleosides, Nucleotides & Nucleic Acids, 1997 - Taylor & Francis
Abstract We synthesized 3′-O-dimethoxytrityl-5′ O-phosphoramidites and 5′-O-
succinates which can be used as monomeric building blocks for the built up of …

Oligodeoxynucleotide analogues containing 3′-deoxy-3′-C-threo-hydroxymethylthymidine: Synthesis, hybridization properties and enzymatic stability

ML Svendsen, J Wengel, O Dahl, F Kirpekar… - Tetrahedron, 1993 - Elsevier
Novel Oligodeoxynucleotide analogues containing 3′-C-threo-methylene phosphodiester
internucleoside linkages were synthesized on automated DNA-synthesizers using the …