Proteomics reveals novel oxidative and glycolytic mechanisms in type 1 diabetic patients' skin which are normalized by kidney-pancreas transplantation
F Folli, V Guzzi, L Perego, DK Coletta, G Finzi… - Plos one, 2010 - journals.plos.org
Background In type 1 diabetes (T1D) vascular complications such as accelerated
atherosclerosis and diffused macro-/microangiopathy are linked to chronic hyperglycemia …
atherosclerosis and diffused macro-/microangiopathy are linked to chronic hyperglycemia …
Importance of identifying novel biomarkers of microvascular damage in type 1 diabetes
ML Marcovecchio - Molecular Diagnosis & Therapy, 2020 - Springer
Microvascular complications of type 1 diabetes, which primarily include diabetic kidney
disease, retinopathy, and neuropathy, are characterized by damage to the microvasculature …
disease, retinopathy, and neuropathy, are characterized by damage to the microvasculature …
High glucose causes distinct expression patterns of primary human skin cells by RNA sequencing
S Zhang, Z Ke, C Yang, P Zhou, H Jiang… - Frontiers in …, 2021 - frontiersin.org
Diabetes-related skin problems represent the most common long-term complications in
diabetes mellitus patients. These complications, which include diabetic dermopathy, diabetic …
diabetes mellitus patients. These complications, which include diabetic dermopathy, diabetic …
Characterization of glycolytic enzymes and pyruvate kinase M2 in type 1 and 2 diabetic nephropathy
OBJECTIVE Elevated glycolytic enzymes in renal glomeruli correlated with preservation of
renal function in the Medalist Study, individuals with≥ 50 years of type 1 diabetes …
renal function in the Medalist Study, individuals with≥ 50 years of type 1 diabetes …
Proteome profiling in the aorta and kidney of type 1 diabetic rats
Diabetes is associated with a number of metabolic and cardiovascular risk factors that
contribute to a high rate of microvascular and macrovascular complications. The risk factors …
contribute to a high rate of microvascular and macrovascular complications. The risk factors …
Diabetes-induced proteome changes throughout development
Background: Diabetes Mellitus (DM) is a multisystemic disease involving the homeostasis of
insulin secretion by the pancreatic islet beta cells (β-cells). It is associated with hypertension …
insulin secretion by the pancreatic islet beta cells (β-cells). It is associated with hypertension …
[HTML][HTML] novel biomarkers for type 2 diabetes
TS Ahluwalia, TO Kilpeläinen, S Singh… - Frontiers in …, 2019 - frontiersin.org
Diabetes Mellitus, commonly known as diabetes, is a complex metabolic disorder
characterized by hyperglycemia over a prolonged period. The prevalence of diabetes is …
characterized by hyperglycemia over a prolonged period. The prevalence of diabetes is …
Proteomic discovery of diabetic nephropathy biomarkers
ML Merchant, JB Klein - Advances in chronic kidney disease, 2010 - Elsevier
Diabetes mellitus (DM) is a complex systemic disease with complications that result from
both genetic predisposition and dysregulated metabolic pathways. It is highly prevalent, with …
both genetic predisposition and dysregulated metabolic pathways. It is highly prevalent, with …
Multi-omics analysis of diabetic nephropathy reveals potential new mechanisms and drug targets
Q Sha, J Lyu, M Zhao, H Li, M Guo, Q Sun - Frontiers in genetics, 2020 - frontiersin.org
Diabetic nephropathy (DN) is one of the most common diabetic complications, which is the
major course of end-stage renal disease (ESRD). However, the systematical molecular …
major course of end-stage renal disease (ESRD). However, the systematical molecular …
Molecular mechanisms of diabetic nephropathy and its therapeutic intervention
S Yamagishi, K Fukami, S Ueda… - Current drug targets, 2007 - ingentaconnect.com
Diabetic nephropathy is a leading cause of end-stage renal failure, which could account for
disabilities and high mortality rates in patients with diabetes. Diabetic nephropathy seems to …
disabilities and high mortality rates in patients with diabetes. Diabetic nephropathy seems to …