Transient receptor potential channels, of the vanilloid subtype (TRPV), act as sensory
mediators, being activated by endogenous ligands, heat, mechanical and osmotic stress …

Recent studies have introduced the importance of transient receptor potential vanilloid
subtype 4 (TRPV4) channels in the regulation of vascular tone. TRPV4 channels are …

Key points The functional roles of the capsaicin receptor, TRPV1, outside of sensory nerves
are unclear. We mapped TRPV1 in the mouse circulation, revealing extensive expression in …

Transient receptor potentials (TRPs) are non-selective cation channels that are widely
expressed in vascular beds. They contribute to the Ca2+ influx evoked by a wide spectrum …

Key points• TRPV1 (transient receptor potential vanilloid 1) channels are found throughout
the body in epithelial cells and in peripheral and central terminals in neurons. They exert a …

Transient receptor potential vanilloid (TRPV) channels are part of the TRP channel
superfamily and named after the first identified member TRPV1, that is sensitive to the …

TRPV4 channels are non-selective cation channels permeable to Ca 2+, Na+, and Mg 2+
ions. Recently, TRPV4 channels have received considerable attention as these channels …

Transient receptor potential vanilloid 4 (TRPV4) ion channels on the endothelial cell
membrane are widely regarded as a crucial Ca 2+ influx pathway that promotes …

BACKGROUND AND PURPOSE The transient receptor potential vanilloid 1 (TRPV1) plays
a role in the activation of sensory neurons by various painful stimuli and is a therapeutic …

Transient receptor potential vanilloid 4 (TRPV4) channels are widely expressed in systemic
tissues and can be activated by many stimuli. TRPV4, a Ca2+-permeable cation channel …