Pharmacokinetics, safety and tolerability of oral semaglutide in subjects with renal impairment

C Granhall, FL Søndergaard, M Thomsen… - Clinical …, 2018 - Springer
Background Semaglutide, a glucagon-like peptide-1 (GLP-1) analogue, has been co-
formulated with the absorption enhancer sodium N-(8-[2-hydroxybenzoyl] amino) caprylate …

Cost-effectiveness analysis of semaglutide 2.4 mg for the treatment of adult patients with overweight and obesity in the United States

N Kim, J Wang, C Burudpakdee, Y Song… - Journal of Managed …, 2022 - jmcp.org
BACKGROUND: The rising prevalence and associated public health burden of obesity has
led to advancements in pharmaceuticals for weight management. Semaglutide 2.4 mg, an …

Oral semaglutide for type 2 diabetes: A systematic review and meta‐analysis

I Avgerinos, T Michailidis, A Liakos… - Diabetes, Obesity …, 2020 - Wiley Online Library
Aim To assess the efficacy and safety of oral semaglutide, a novel glucagon‐like peptide‐1
receptor agonist, for patients with type 2 diabetes. Methods We searched Medline, Embase …

Real‐world effectiveness and safety of oral semaglutide in people living with type 2 diabetes: A nationwide multicentre retrospective observational study (ENDO2S …

O Moreno‐Pérez, R Reyes‐Garcia… - Diabetes, Obesity …, 2024 - Wiley Online Library
1 BACKGROUND Type 2 diabetes guidelines recommend glucagon-like peptide-1 receptor
agonists (GLP-1 RAs) and/or sodium-glucose co-transporter-2 inhibitors for people living …

Safety and efficacy of semaglutide once weekly vs sitagliptin once daily, both as monotherapy in J apanese people with type 2 diabetes

Y Seino, Y Terauchi, T Osonoi, D Yabe… - Diabetes, obesity …, 2018 - Wiley Online Library
Aims To assess the safety and efficacy of monotherapy with once‐weekly subcutaneous (sc)
semaglutide vs sitagliptin in Japanese people with type 2 diabetes (T2D). Methods In this …

Semaglutide for the treatment of type 2 diabetes mellitus

KE Miles, JL Kerr - Journal of Pharmacy Technology, 2018 - journals.sagepub.com
Objective: To detail studies investigating the efficacy/safety of semaglutide as a glucagon-
like peptide-1 receptor agonist (GLP-1 RA) in the treatment of type 2 diabetes mellitus. Data …

High-dose once-weekly semaglutide: a new option for obesity management

CL Bradley, SM McMillin, AY Hwang… - Annals of …, 2022 - journals.sagepub.com
Objective To review the pharmacology, efficacy, and safety of high-dose once-weekly
semaglutide for chronic weight management. Data Sources PubMed/MEDLINE and …

Once‐weekly semaglutide use in patients with type 2 diabetes: Results from the SURE France multicentre, prospective, observational study

K Mohammedi, N Belhatem… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aims Real‐world data are required to support glucagon‐like peptide‐1 receptor agonist use
in type 2 diabetes (T2D). SURE France assessed once‐weekly semaglutide in adults with …

Adverse drug reactions of GLP-1 agonists: a systematic review of case reports

R Shetty, FT Basheer, PG Poojari, G Thunga… - Diabetes & Metabolic …, 2022 - Elsevier
Background and aim The importance of glucagon-like peptide-1 (GLP-1) agonists is
increasing because of its blood sugar controlling and weight loss properties. The data …

Benefit-risk assessment of obesity drugs: focus on glucagon-like peptide-1 receptor agonists

RM Christensen, CR Juhl, SS Torekov - Drug safety, 2019 - Springer
The prevalence of obesity and related comorbidities is increasing worldwide. Furthermore,
clinically meaningful body weight losses has proven difficult to achieve and especially to …