During the last decade, the endothelial-to-mesenchymal transition (EndMT) process has
attracted considerable attention due to associations with the onset of certain diseases, such …

Matrix metalloproteinases (MMPs) are a family of zinc dependent endopeptidases whose
main function is to degrade and deposit structural proteins within the extracellular matrix …

Extracellular matrix proteins form the basic structure of blood vessels. Along with providing
basic structural support to blood vessels, matrix proteins interact with different sets of …

The vasculature is composed of different blood vessel types that range from the small
diameter capillaries and postcapillary venules to the larger and more complex arterioles …

The extracellular matrix (ECM) is the noncellular component present within all tissues and
organs, and provides not only essential physical scaffolding for the cellular constituents but …

There is growing interest in the role of matrix metalloproteinasesin vascular diseases. These
conditions are often characterized by excessive tissue remodelling, and increased matrix …

The extracellular matrix plays a critical role in orchestrating the events necessary for wound
healing, muscle repair, morphogenesis, new blood vessel growth, and cancer invasion. In …

Inflammatory process is essential for the initiation and progression of vascular remodeling,
entailing degradation and reorganization of the extra-cellular matrix (ECM) scaffold of the …

Connective tissue remodeling is achieved by a complex process involving several cell types,
a plethora of growth factors, cytokines, chemokines and turnover of extracellular matrix …

Background—Cardiovascular disease is the leading cause of mortality in chronic kidney
disease patients on maintenance dialysis. Given the importance of matrix metalloproteinase …