Imprinted antibody responses against SARS-CoV-2 Omicron sublineages

YJ Park, D Pinto, AC Walls, Z Liu, A De Marco… - Science, 2022 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages carry
distinct spike mutations resulting in escape from antibodies induced by previous infection or …

Omicron BA. 1 breakthrough infection drives cross-variant neutralization and memory B cell formation against conserved epitopes

J Quandt, A Muik, N Salisch, BG Lui, S Lutz… - Science …, 2022 - science.org
Omicron is the evolutionarily most distinct severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) variant of concern (VOC) to date. We report that Omicron BA. 1 breakthrough …

Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariants

B Ju, Q Zhang, Z Wang, ZQ Aw, P Chen, B Zhou… - Nature …, 2023 - nature.com
The omicron variants of SARS-CoV-2 have substantial ability to escape infection-and
vaccine-elicited antibody immunity. Here, we investigated the extent of such escape in nine …

Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants

K Wang, Z Jia, L Bao, L Wang, L Cao, H Chi, Y Hu, Q Li… - Nature, 2022 - nature.com
Abstract Omicron (B. 1.1. 529), the most heavily mutated SARS-CoV-2 variant so far, is
highly resistant to neutralizing antibodies, raising concerns about the effectiveness of …

[PDF][PDF] Antibody evasion of SARS-CoV-2 Omicron BA. 1, BA. 1.1, BA. 2, and BA. 3 sub-lineages

J Ai, X Wang, X He, X Zhao, Y Zhang, Y Jiang, M Li… - Cell host & …, 2022 - cell.com
Summary The SARS-CoV-2 Omicron variant has evolved into four sub-lineages—BA. 1, BA.
1.1, BA. 2, and BA. 3—with BA. 2 becoming dominant worldwide. We and others have …

Vaccines elicit highly conserved cellular immunity to SARS-CoV-2 Omicron

J Liu, A Chandrashekar, D Sellers, J Barrett… - Nature, 2022 - nature.com
The highly mutated SARS-CoV-2 Omicron (B. 1.1. 529) variant has been shown to evade a
substantial fraction of neutralizing antibody responses elicited by current vaccines that …

[PDF][PDF] Progressive loss of conserved spike protein neutralizing antibody sites in Omicron sublineages is balanced by preserved T cell immunity

A Muik, BG Lui, J Quandt, H Diao, Y Fu, M Bacher… - Cell Reports, 2023 - cell.com
Evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron
variant has led to the emergence of sublineages with different patterns of neutralizing …

Immunological imprinting shapes the specificity of human antibody responses against SARS-CoV-2 variants

TS Johnston, SH Li, MM Painter, RK Atkinson… - Immunity, 2024 - cell.com
The spike glycoprotein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
continues to accumulate substitutions, leading to breakthrough infections of vaccinated …

Omicron spike function and neutralizing activity elicited by a comprehensive panel of vaccines

JE Bowen, A Addetia, HV Dang, C Stewart, JT Brown… - Science, 2022 - science.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of
concern comprises several sublineages, with BA. 2 and BA. 2.12. 1 having replaced the …

Antibody evasion by SARS-CoV-2 Omicron subvariants BA. 2.12. 1, BA. 4 and BA. 5

Q Wang, Y Guo, S Iketani, MS Nair, Z Li, H Mohri… - Nature, 2022 - nature.com
Abstract SARS-CoV-2 Omicron subvariants BA. 2.12. 1 and BA. 4/5 have surged notably to
become dominant in the United States and South Africa, respectively,. These new …