Black ginseng ameliorates cellular senescence via p53-p21/p16 pathway in aged mice

SJ Lee, DY Lee, JF O'Connell, JM Egan, Y Kim - Biology, 2022 - mdpi.com
Simple Summary The goal of this study was to examine if BG impacts the aging process,
specifically cellular senescence, using in vitro and aged mouse models. Primary mouse …

Red Ginseng Attenuates the Hepatic Cellular Senescence in Aged Mice

DY Lee, J Arndt, JF O'Connell, JM Egan, Y Kim - Biology, 2024 - mdpi.com
Simple Summary The aim of this study was to explore the potential impact of red ginseng
(RG) on age-associated cellular senescence through in vitro, ex vivo, and 19-month-old …

Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota

X Peng, M Hao, Y Zhao, Y Cai, X Chen, H Chen… - Phytomedicine, 2021 - Elsevier
Background Panax ginseng (PG) and red ginseng (RG) are considered to be effective anti-
aging treatments. However, evidence of their therapeutic mechanisms and difference in anti …

Research progress on the anti-aging potential of the active components of ginseng

J Su, Q Su, S Hu, X Ruan, S Ouyang - Nutrients, 2023 - mdpi.com
Aging is a cellular state characterized by a permanent cessation of cell division and evasion
of apoptosis. DNA damage, metabolic dysfunction, telomere damage, and mitochondrial …

Korean red ginseng plays an anti-aging role by modulating expression of aging-related genes and immune cell subsets

KK Shin, YS Yi, JK Kim, H Kim, MA Hossain, JH Kim… - Molecules, 2020 - mdpi.com
Despite previous reports of anti-aging effects of Korean red ginseng (KRG), the underlying
mechanisms remain poorly understood. Therefore, this study investigated possible …

[HTML][HTML] Korean red ginseng tonic extends lifespan in D. melanogaster

MS Kim - Biomolecules & Therapeutics, 2013 - ncbi.nlm.nih.gov
Aging is the single most important risk factor that increases susceptibility to many forms of
diseases. As such, much effort has been put forward to elucidate the mechanisms behind …

Ginsenoside Rb1 retards aging process by regulating cell cycle, apoptotic pathway and metabolism of aging mice

S Yu, H Xia, Y Guo, X Qian, X Zou, H Yang… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Ginsenoside Rb1 (GRb1), an active ingredient of
traditional Chinese medicine Panax ginseng CA Meyer, has displayed various activities …

Ginsenoside Rg1 protects against d-galactose induced fatty liver disease in a mouse model via FOXO1 transcriptional factor

R Qi, R Jiang, H Xiao, Z Wang, S He, L Wang, Y Wang - Life Sciences, 2020 - Elsevier
Aims Rg1 is the most active component of traditional Chinese medicine ginseng, having anti-
aging and anti-oxidative stress features in multiple organs. Cellular senescence of …

Ginseng under forest exerts stronger anti-aging effects compared to garden ginseng probably via regulating PI3K/AKT/mTOR pathway, SIRT1/NF-κB pathway and …

M Hao, C Ding, X Peng, H Chen, L Dong, Y Zhang… - Phytomedicine, 2022 - Elsevier
Background Ginseng is deemed to be an effective anti-aging therapy. Evidence for
differences in representative active ingredients and anti-aging effects between garden …

[HTML][HTML] Ginsenoside Rb2 suppresses cellular senescence of human dermal fibroblasts by inducing autophagy

KE Yang, SB Nam, M Jang, J Park, GE Lee… - Journal of Ginseng …, 2023 - Elsevier
Abstract Background Ginsenoside Rb2, a major active component of Panax ginseng, has
various physiological activities, including anticancer and anti-inflammatory effects. However …