Bronchial asthma can be a chronic and debilitating respiratory disease. Increasing evidence
suggests that airway epithelial cells and their products may in part be responsible for the …

Comparative efficacy and safety of inhaled corticosteroids in asthma. - Abstract - Europe
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Glucocorticoids are highly effective in the control of asthma and suppression of airway
inflammation. The cellular and molecular mechanisms involved in the anti-inflammatory …

The mechanism of corticosteroid resistance in bronchial asthma has been studied
b\determining the rank order of potency for different corticosteroids In inhibiting the …

Corticosteroids have been used in the treatment of asthma since 1950 when the first
preparations of biosynthetically derived analogs of the adrenal cortical hormones became …

Rationale: Patients with severe asthma (SA) are less responsive to the beneficial effects of
corticosteroid (CS) therapy, and relative CS insensitivity has been shown in airway smooth …

The glucocorticoid molecule diffuses passively through the cell membrane into the
cytoplasm ofthe cell. There is no membrane receptor for glucocorticosteroids. In the …

Corticosteroids produce a marked improvement in clinical parameters in most asthmatic
patients; in contrast, corticosteroids have little effect on lung function measurements in …

In children, an inhaled glucocorticoid is currently the medication of choice for the long-term
control of persistent asthma. Inhaled glucocorticoids are significantly more effective than …

Glucocorticoids are the mainstay of asthma therapy. They are primarily used to suppress
airway inflammation, which is the central pathological change in asthmatic patients' airways …