It is now widely accepted that the development of atherosclerotic lesions involves a chronic
inflammatory response that includes both innate and adaptive immune mechanisms …

It has been known for over 150 years that hallmarks of inflammation can be observed in the
wall of atherosclerotic vessels. It was, however, not clear if this inflammation is the cause or …

The notion that inflammation contributes to atherosclerosis has now gained considerable
currency. Inflammation participates in atherosclerosis inception, progression, and thrombotic …

Recent studies have highlighted the role of inflammatory mediators and the cells of the
innate and adaptive immune response in the initiation, growth and rupture of atherosclerotic …

Modern-day treatment of atherosclerosis has arisen primarily from an understanding of the
epidemiology of the disease rather than its pathophysiology, in that risk factors have …

Inflammation is now recognized as being pivotal in the pathogenesis of atherosclerosis. This
review highlights key concepts in our current understanding of the role of inflammation in the …

The concept that inflammation participates pivotally in the pathogenesis of atherosclerosis
and its complications has gained considerable attention, but has not yet entered clinical …

Experimental work has elucidated molecular and cellular pathways of inflammation that
promote atherosclerosis. Unraveling the roles of cytokines as inflammatory messengers …

The causal role of inflammation at the core of endothelial dysfunction, atherosclerosis and
cardiovascular diseases is discussed. Atherosclerosis is an arterial disease characterized …

Our current understanding of the vascular biology of atherogenesis and its clinical
manifestations suggests a pathophysiology that is much more complex than mere lipid …