Neuropilin (Nrp) receptors function as essential cell surface receptors for the Vascular
Endothelial Growth Factor (VEGF) family of proangiogenic cytokines and the semaphorin 3 …

Angiogenesis involves endothelial cell differentiation, proliferation, migration and cord
formation, which lead to tubulogenesis to form vessels. One group of growth factor receptors …

The development of functional blood and lymphatic vessels requires spatio-temporal
coordination of the production and release of growth factors such as vascular endothelial …

Vascular endothelial growth factor (VEGF)–A regulates vascular development and
angiogenesis. VEGF isoforms differ in ability to bind coreceptors heparan sulfate (HS) and …

Vascular endothelial growth factors (VEGFs) regulate blood and lymphatic vessel
development and homeostasis but also have profound effects on neural cells. VEGFs are …

In development and disease, vascular endothelial growth factor (VEGF) regulates the
expansion of the vascular tree. In response to hypoxia, VEGF promotes new capillary …

Co‐expression of NRP1 and (VEGFR‐2) KDR on the surface of endothelial cells (EC)
enhances VEGF165 binding to KDR and EC chemotaxis in response to VEGF165 …

Essential roles of NRP1 (neuropilin-1) in cardiovascular development and in neuronal axon
targeting during embryogenesis are thought to be mediated primarily through binding of …

Endothelial cells express neuropilin 1 (NRP1), endoglin (ENG) and vascular endothelial
growth factor receptor 2 (VEGFR2), which regulate VEGF-A-mediated vascular development …

All known splice isoforms of vascular endothelial growth factor A (VEGF-A) can bind to the
receptor tyrosine kinases VEGFR-1 and VEGFR-2. We focus here on VEGF-A121a and …