[HTML][HTML] A multiscale computational model predicts distribution of anti-angiogenic isoform VEGF165b in peripheral arterial disease in human and mouse
Angiogenesis is the growth of new blood vessels from pre-existing microvessels. Peripheral
arterial disease (PAD) is caused by atherosclerosis that results in ischemia mostly in the …
arterial disease (PAD) is caused by atherosclerosis that results in ischemia mostly in the …
The splice variants of vascular endothelial growth factor (VEGF) and their receptors
CJ Robinson, SE Stringer - Journal of cell science, 2001 - journals.biologists.com
Vascular endothelial growth factor (VEGF) is a secreted mitogen highly specific for cultured
endothelial cells. In vivo VEGF induces microvascular permeability and plays a central role …
endothelial cells. In vivo VEGF induces microvascular permeability and plays a central role …
[HTML][HTML] Vascular endothelial growth factor (VEGF)/VEGF-C mosaic molecules reveal specificity determinants and feature novel receptor binding patterns
Vascular endothelial growth factors (VEGFs) and their receptors play key roles in
angiogenesis and lymphangiogenesis. VEGF activates VEGF receptor-1 (VEGFR-1) and …
angiogenesis and lymphangiogenesis. VEGF activates VEGF receptor-1 (VEGFR-1) and …
[HTML][HTML] Characterization of a bicyclic peptide neuropilin-1 (NP-1) antagonist (EG3287) reveals importance of vascular endothelial growth factor exon 8 for NP-1 …
H Jia, A Bagherzadeh, B Hartzoulakis, A Jarvis… - Journal of Biological …, 2006 - ASBMB
Neuropilin-1 (NP-1) is a receptor for vascular endothelial growth factor-A 165 (VEGF-A 165)
in endothelial cells. To define the role of NP-1 in the biological functions of VEGF, we …
in endothelial cells. To define the role of NP-1 in the biological functions of VEGF, we …
Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A
M Narazaki, G Tosato - Blood, 2006 - ashpublications.org
Neuropilin-1 (Npn-1) is a receptor shared by class 3 semaphorins and heparin-binding
forms of vascular endothelial growth factor (VEGF), protein families that regulate endothelial …
forms of vascular endothelial growth factor (VEGF), protein families that regulate endothelial …
[HTML][HTML] A compartment model of VEGF distribution in humans in the presence of soluble VEGF receptor-1 acting as a ligand trap
Vascular endothelial growth factor (VEGF), through its activation of cell surface receptor
tyrosine kinases including VEGFR1 and VEGFR2, is a vital regulator of stimulatory and …
tyrosine kinases including VEGFR1 and VEGFR2, is a vital regulator of stimulatory and …
Structural studies of neuropilin‐2 reveal a zinc ion binding site remote from the vascular endothelial growth factor binding pocket
YCI Tsai, C Fotinou, R Rana, T Yelland… - The FEBS …, 2016 - Wiley Online Library
Neuropilin‐2 is a transmembrane receptor involved in lymphangiogenesis and neuronal
development. In adults, neuropilin‐2 and its homologous protein neuropilin‐1 have been …
development. In adults, neuropilin‐2 and its homologous protein neuropilin‐1 have been …
Signal transduction by VEGF receptor-1 wild type and mutant proteins
N Ito, K Huang, L Claesson-Welsh - Cellular signalling, 2001 - Elsevier
The role of the vascular endothelial growth factor receptor-1 (VEGFR-1) in endothelial cell
function is unclear. We have previously identified four tyrosine phosphorylation sites in the C …
function is unclear. We have previously identified four tyrosine phosphorylation sites in the C …
[HTML][HTML] The role of heterodimerization between VEGFR-1 and VEGFR-2 in the regulation of endothelial cell homeostasis
VEGF-A activity is tightly regulated by ligand and receptor availability. Here we investigate
the physiological function of heterodimers between VEGF receptor-1 (VEGFR-1; Flt-1) and …
the physiological function of heterodimers between VEGF receptor-1 (VEGFR-1; Flt-1) and …
Characterization of receptor binding kinetics for vascular endothelial growth factor-A using SPR
Angiogenesis is a highly regulated process orchestrated, in large part, by the vascular
endothelial growth factor-A (VEGF-A) system of ligands and receptors. Considerable effort …
endothelial growth factor-A (VEGF-A) system of ligands and receptors. Considerable effort …