RAF kinase inhibitor-independent constitutive activation of Yes-associated protein 1 promotes tumor progression in thyroid cancer
SE Lee, JU Lee, MH Lee, MJ Ryu, SJ Kim, YK Kim… - Oncogenesis, 2013 - nature.com
The transcription coactivator Yes-associated protein 1 (YAP1) is regulated by the Hippo
tumor suppressor pathway. However, the role of YAP1 in thyroid cancer, which is frequently …
tumor suppressor pathway. However, the role of YAP1 in thyroid cancer, which is frequently …
[HTML][HTML] Yes-associated protein 1 promotes papillary thyroid cancer cell proliferation by activating the ERK/MAPK signaling pathway
T Liao, D Wen, B Ma, JQ Hu, N Qu, RL Shi, L Liu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Yes-associated protein 1 (YAP1) stimulates cell proliferation, epithelial-to-
mesenchymal transition, invasion and metastasis in several cancers. Here, we investigated …
mesenchymal transition, invasion and metastasis in several cancers. Here, we investigated …
Down-regulation of Yes Associated Protein 1 expression reduces cell proliferation and clonogenicity of pancreatic cancer cells
CH Diep, KM Zucker, G Hostetter, A Watanabe, C Hu… - PloS one, 2012 - journals.plos.org
Background The Hippo pathway regulates organ size by inhibiting cell proliferation and
promoting cell apoptosis upon its activation. The Yes Associated Protein 1 (YAP1) is a …
promoting cell apoptosis upon its activation. The Yes Associated Protein 1 (YAP1) is a …
Yes-associated protein 1 is a novel calcium sensing receptor target in human parathyroid tumors
GS Tavanti, C Verdelli, A Morotti, P Maroni… - International Journal of …, 2021 - mdpi.com
The Hippo pathway is involved in human tumorigenesis and tissue repair. Here, we
investigated the Hippo coactivator Yes-associated protein 1 (YAP1) and the kinase large …
investigated the Hippo coactivator Yes-associated protein 1 (YAP1) and the kinase large …
YAP 1 overexpression is associated with poor prognosis of breast cancer patients and induces breast cancer cell growth by inhibiting PTEN
L Guo, Y Chen, J Luo, J Zheng, G Shao - FEBS open bio, 2019 - Wiley Online Library
YES‐associated protein 1 (YAP 1) plays a key role as a transcriptional coactivator in the
Hippo tumor suppressor pathway. YAP 1 is overexpressed in a variety of cancers and is …
Hippo tumor suppressor pathway. YAP 1 is overexpressed in a variety of cancers and is …
Expression of Yes-associated protein 1 and its clinical significance in ovarian serous cystadenocarcinoma
SY Cho, K Kim, MS Park, MY Jang… - Oncology …, 2017 - spandidos-publications.com
Abstract Yes-associated protein 1 (YAP1) is a key transcriptional regulator in the Hippo
signaling pathway that plays a critical role in the development and progression of several …
signaling pathway that plays a critical role in the development and progression of several …
Knockdown of YAP inhibits growth in Hep-2 laryngeal cancer cells via epithelial-mesenchymal transition and the Wnt/β-catenin pathway
X Tang, Y Sun, G Wan, J Sun, J Sun, C Pan - BMC cancer, 2019 - Springer
Background Yes-associated protein (YAP) plays a crucial role in tumour development and it
is the main effector of the Hippo signalling pathway. However, the mechanism underlying …
is the main effector of the Hippo signalling pathway. However, the mechanism underlying …
The deubiquitinating enzyme UCHL3 promotes anaplastic thyroid cancer progression and metastasis through Hippo signaling pathway
J Tang, Q Yang, C Mao, D Xiao, S Liu, L Xiao… - Cell Death & …, 2023 - nature.com
Yes-associated protein (YAP) is one of major key effectors of the Hippo pathway and the
mechanism supporting abnormal YAP expression in Anaplastic thyroid carcinoma (ATC) …
mechanism supporting abnormal YAP expression in Anaplastic thyroid carcinoma (ATC) …
[HTML][HTML] Increased expression of YAP1 in prostate cancer correlates with extraprostatic extension
Objective: Yes associated protein 1 (YAP1) is a member of the Hippo pathway, acting as a
transcriptional coactivator. To elucidate the role of YAP1 and phosphorylated (p) YAP1 in …
transcriptional coactivator. To elucidate the role of YAP1 and phosphorylated (p) YAP1 in …
Yes-associated protein 1 exhibits oncogenic property in gastric cancer and its nuclear accumulation associates with poor prognosis
Abstract Purpose: Yes-associated protein 1 (YAP1) is a multifunctional protein that can
interact with different transcription factors to activate gene expression. The role of YAP1 in …
interact with different transcription factors to activate gene expression. The role of YAP1 in …