Molecular and pathologic aspects of endometrial carcinogenesis

JL Hecht, GL Mutter - Journal of clinical oncology, 2006 - ascopubs.org
Endometrial cancer is the most common gynecological malignancy, with 41,000 new cases
projected in the United States for 2006. Two different clinicopathologic subtypes are …

Endometrial carcinoma: pathology and genetics

J Prat, A Gallardo, M Cuatrecasas, L Catasús - Pathology, 2007 - Taylor & Francis
In the Western world, endometrial carcinoma is the most common malignant tumour of the
female genital tract and the fourth most common cancer in women after carcinomas of …

Endometrial carcinoma: molecular alterations involved in tumor development and progression

A Yeramian, G Moreno-Bueno, X Dolcet, L Catasus… - Oncogene, 2013 - nature.com
In the western world, endometrial carcinoma (EC) is the most common cancer of the female
genital tract. The annual incidence has been estimated at 10–20 per 100 000 women. Two …

Molecular genetic pathways in various types of endometrial carcinoma: from a phenotypical to a molecular-based classification

SF Lax - Virchows Archiv, 2004 - Springer
Two types of endometrial carcinoma are distinguished with respect to biology and clinical
course. Type-I carcinoma is related to hyperestrogenism by association with endometrial …

Molecular profiling of endometrial malignancies

N Samarnthai, K Hall, IT Yeh - Obstetrics and gynecology …, 2010 - Wiley Online Library
Molecular profiling of endometrial neoplasms reveals genetic changes in endometrial
carcinomas that support the dualistic model, in which type I carcinomas are estrogen …

Pathology of endometrial carcinoma

SF Lax - Molecular Genetics of Endometrial Carcinoma, 2017 - Springer
On a clinicopathological and molecular level, two distinctive types of endometrial carcinoma,
type I and type II, can be distinguished. Endometrioid carcinoma, the typical type I …

The genomics and genetics of endometrial cancer

AJ O'Hara, DW Bell - Advances in genomics and genetics, 2012 - Taylor & Francis
Most sporadic endometrial cancers (ECs) can be histologically classified as endometrioid,
serous, or clear cell. Each histotype has a distinct natural history, clinical behavior, and …

Molecular carcinogenesis of endometrial cancer

FS Liu - Taiwanese Journal of obstetrics and Gynecology, 2007 - Elsevier
In 1983, Bokhman proposed a dualistic model of endometrial tumorigenesis based on the
clinical observations and clinicopathologic correlations. The majority of endometrial cancers …

The molecular biology of endometrial cancers and the implications for pathogenesis, classification, and targeted therapies

N Bansal, V Yendluri, RM Wenham - Cancer control, 2009 - journals.sagepub.com
Background Understanding and identifying molecular biology and genetics of endometrial
cancer are central to the development of novel therapies. This article reviews the molecular …

Molecular genetics of endometrial carcinoma

DW Bell, LH Ellenson - Annual Review of Pathology …, 2019 - annualreviews.org
Endometrial cancer is the most commonly diagnosed gynecologic malignancy in the United
States. Endometrioid endometrial carcinomas constitute approximately 85% of newly …