Accumulating findings during the past decades have demonstrated that the hypothalamic
arcuate kisspeptin neurons are supposed to be responsible for pulsatile release of …

Uncovering the central mechanism underlying mammalian reproduction is warranted to
develop new therapeutic approaches for reproductive disorders in humans and domestic …

In the past decade since kisspeptin/neurokinin B/dynorphin (KNDy) cells were first identified
in the mammalian hypothalamus, a plethora of new research has emerged adding insights …

Increasing evidence accumulated during the past two decades has demonstrated that the
then-novel kisspeptin, which was discovered in 2001, the known neuropeptides neurokinin …

Highly sophisticated and synchronized interactions of various cells and hormonal signals
are required to make organisms competent for reproduction. GnRH neurons act as a …

Reproductive function is driven by the hormonal interplay between the gonads and brain–
pituitary axis. Gonadotropin-releasing hormone (GnRH) is released in a pulsatile manner …

A major advance in neuroendocrinology in the past 20 years was the discovery that
kisspeptin neurons of the arcuate nucleus (ARC), termed KNDy neurons because of their co …

Pulsatile GnRH release is essential for normal reproductive function. Kisspeptin secreting
neurons found in the arcuate nucleus, known as KNDy neurons for co-expressing …

The concept that different systems control episodic and surge secretion of gonadotropin‐
releasing hormone (GnRH) was well established by the time that GnRH was identified and …

Accumulating evidence suggests that kisspeptin neurons in the arcuate nucleus (ARC),
which coexpress neurokinin B and dynorphin, are involved in gonadotropin-releasing …