Abstract Background The results of Randomized Controlled Trials (RCTs) on time-to-event
outcomes that are usually reported are median time to events and Cox Hazard Ratio. These …

Background: The hazard ratio (HR) is the most appropriate measure for time to event
outcomes such as survival. In systematic reviews, HRs can be calculated either from the raw …

In epidemiologic studies and clinical trials with time‐dependent outcome (for instance death
or disease progression), survival curves are used to describe the risk of the event over time …

Background When applying secondary analysis on published survival data, it is critical to
obtain each patient's raw data, because the individual patient data (IPD) approach has been …

Survival analysis is a set of methods used to study the time between enrollment in a study
and the occurrence of an event of interest. Two methods are commonly used: actuarial life …

Survival plots of time-to-event data are a key component for reporting results of many clinical
trials (and cohort studies). However, mistakes and distortions often arise in the display and …

Background Mean costs and quality-adjusted-life-years are central to the cost-effectiveness
of health technologies. They are often calculated from time to event curves such as for …

Analysis of time-to-event ('survival') data requires two pieces of data that are taken into
account simultaneously: the time period for which follow-up was available, and the status at …

Meta‐analyses aim to provide a full and comprehensive summary of related studies which
have addressed a similar question. When the studies involve time to event (survival‐type) …

For designing, monitoring, and analyzing a longitudinal study with an event time as the
outcome variable, the restricted mean event time (RMET) is an easily interpretable, clinically …