[HTML][HTML] Advances in indole-containing alkaloids as potential anticancer agents by regulating autophagy

ML Luo, W Huang, HP Zhu, C Peng, Q Zhao… - Biomedicine & …, 2022 - Elsevier
Cancer is a leading cause of death worldwide, and cancer development is often associated
with disturbances in the autophagy process. Autophagy is a catabolic process involved in …

[HTML][HTML] New visions on natural products and cancer therapy: Autophagy and related regulatory pathways

A Martelli, M Omrani, M Zarghooni, V Citi, S Brogi… - Cancers, 2022 - mdpi.com
Simple Summary In the past few years, clinical as well as regular scientists have been
paying attention to medicinal applications of natural products. There are several …

[HTML][HTML] Targeting autophagy with natural products as a potential therapeutic approach for cancer

MAA Al-Bari, Y Ito, S Ahmed, N Radwan… - International journal of …, 2021 - mdpi.com
Macro-autophagy (autophagy) is a highly conserved eukaryotic intracellular process of self-
digestion caused by lysosomes on demand, which is upregulated as a survival strategy …

Seeking new anti-cancer agents from autophagy-regulating natural products

F Hua, S Shang, ZW Hu - Journal of Asian natural products …, 2017 - Taylor & Francis
Natural products are an important original source of many widely used drugs, including anti-
cancer drugs. Early research efforts for seeking anti-cancer therapy from the natural …

Plant natural compounds: targeting pathways of autophagy as anti‐cancer therapeutic agents

X Zhang, LX Chen, L Ouyang, Y Cheng… - Cell proliferation, 2012 - Wiley Online Library
Natural compounds derived from plant sources are well characterized as possessing a wide
variety of remarkable anti‐tumour properties, for example modulating programmed cell …

[HTML][HTML] Anthraquinones and autophagy–Three rings to rule them all?

J Deitersen, DH El-Kashef, P Proksch… - Bioorganic & medicinal …, 2019 - Elsevier
In order to overcome therapy resistance in cancer, scientists search in nature for novel lead
structures for the development of improved chemotherapeutics. Anthraquinones belong to a …

Indole alkaloids from marine resources: Understandings from therapeutic point of view to treat cancers

F Islam, Z Dehbia, M Zehravi, R Das… - Chemico-Biological …, 2023 - Elsevier
Cancer is the leading cause of mortality all over the world. Scientific investigation has
demonstrated that disruptions in the process of autophagy are frequently interrelated with …

Phytochemicals as potent modulators of autophagy for cancer therapy

MA Moosavi, A Haghi, M Rahmati, H Taniguchi… - Cancer Letters, 2018 - Elsevier
The dysregulation of autophagy is involved in the pathogenesis of a broad range of
diseases, and accordingly universal research efforts have focused on exploring novel …

[HTML][HTML] Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells

BYK Law, WK Chan, SW Xu, JR Wang, LP Bai, L Liu… - Scientific reports, 2014 - nature.com
Resistance of cancer cells to chemotherapy is a significant problem in oncology and the
development of sensitising agents or small-molecules with new mechanisms of action to kill …

[HTML][HTML] Natural compounds from herbs that can potentially execute as autophagy inducers for cancer therapy

SR Lin, YS Fu, MJ Tsai, H Cheng, CF Weng - International Journal of …, 2017 - mdpi.com
Accumulated evidence indicates that autophagy is a response of cancer cells to various anti-
cancer therapies. Autophagy is designated as programmed cell death type II, and is …