In vivo molecular‐genetic imaging

RG Blasberg… - Journal of Cellular …, 2002 - Wiley Online Library
Noninvasive in vivo molecular‐genetic imaging has developed over the past decade and
involves nuclear (PET, gamma camera), magnetic resonance, and in vivo optical imaging …

PET-based molecular imaging in neuroscience

AH Jacobs, H Li, A Winkeler, R Hilker, C Knoess… - European journal of …, 2003 - Springer
Positron emission tomography (PET) allows non-invasive assessment of physiological,
metabolic and molecular processes in humans and animals in vivo. Advances in detector …

PET imaging of gene expression

R Blasberg - European journal of cancer, 2002 - Elsevier
Noninvasive in vivo molecular imaging has developed over the past decade and involves
nuclear (Positron emission tomography (PET), gamma camera), magnetic resonance, and in …

In vivo imaging of gene delivery and expression

A Bogdanov, R Weissleder - Trends in Biotechnology, 2002 - cell.com
Recent progress in the development of high-resolution imaging techniques and reporter
probes is expected to revolutionize molecular imaging research in animal models of human …

In vivo molecular-genetic imaging: multi-modality nuclear and optical combinations

RG Blasberg - Nuclear medicine and biology, 2003 - Elsevier
Multi-modality, noninvasive in vivo imaging is increasingly being used in molecular-genetic
studies and will soon become the standard approach for reporter gene imaging studies in …

In vivo imaging of gene expression: MR and optical technologies

C Bremer, R Weissleder - Academic Radiology, 2001 - Elsevier
With the ability to readily engineer genes, create knock-in and knock-out models of human
disease, and replace and insert genes in clinical trials of gene therapy, it has become clear …

In vivo imaging of gene expression

DC Sullivan, JM Hoffman - Seminars in Radiation Oncology, 2001 - Elsevier
Imaging of gene expression is increasingly essential for cancer diagnosis, prediction of
tumor response to various available therapies, and for monitoring response to therapy …

Reporter gene imaging: potential impact on therapy

I Serganova, R Blasberg - Nuclear medicine and biology, 2005 - Elsevier
Positron emission tomography (PET)-based molecular-genetic imaging in living organisms
has enjoyed exceptional growth over the past 5 years; this is particularly striking since it has …

Imaging transgene expression with radionuclide imaging technologies

SS Gambhir, HR Herschman, SR Cherry, JR Barrio… - Neoplasia, 2000 - Elsevier
A variety of imaging technologies are being investigated as tools for studying gene
expression in living subjects. Noninvasive, repetitive and quantitative imaging of gene …

Molecular imaging in living subjects: seeing fundamental biological processes in a new light

TF Massoud, SS Gambhir - Genes & development, 2003 - genesdev.cshlp.org
Morphological observations have driven the course of biology ever since the first
microscope was built in the late sixteenth century. Molecular imaging is a rapidly emerging …