Genotype‐positive status is associated with poor prognoses in patients with left ventricular noncompaction cardiomyopathy

S Li, C Zhang, N Liu, H Bai, C Hou, J Wang… - Journal of the …, 2018 - Am Heart Assoc
Background Left ventricular noncompaction cardiomyopathy (LVNC) is a genetically and
phenotypically heterogeneous disease. This study aims to investigate the genetic basis and …

[HTML][HTML] Reduced systolic function and not genetic variants determine outcome in pediatric and adult left ventricular noncompaction cardiomyopathy

A Schultze-Berndt, J Kühnisch, C Herbst… - Frontiers in …, 2021 - frontiersin.org
Background: Left ventricular noncompaction cardiomyopathy (LVNC CMP) is a genetic
cardiomyopathy. Genotype-phenotype correlation and clinical outcome of genetic variants in …

[HTML][HTML] Genetic landscape in Russian patients with familial left ventricular noncompaction

AN Meshkov, RP Myasnikov, AV Kiseleva… - Frontiers in …, 2023 - frontiersin.org
Background Left ventricular noncompaction (LVNC) cardiomyopathy is a disorder that can
be complicated by heart failure, arrhythmias, thromboembolism, and sudden cardiac death …

Multiple genetic variants in adolescent patients with left ventricular noncompaction cardiomyopathy

S Liu, Y Xie, H Zhang, Z Feng, J Huang, J Huang… - International Journal of …, 2020 - Elsevier
Background Left ventricular noncompaction cardiomyopathy (LVNC) is a primary
cardiomyopathy with an unclear aetiology. The clinical symptoms range from asymptomatic …

Clinical genetics and outcome of left ventricular non-compaction cardiomyopathy

F Sedaghat-Hamedani, J Haas, F Zhu… - European heart …, 2017 - academic.oup.com
Aims In this study, we aimed to clinically and genetically characterize LVNC patients and
investigate the prevalence of variants in known and novel LVNC disease genes. Introduction …

Targeted panel sequencing in adult patients with left ventricular non‐compaction reveals a large genetic heterogeneity

P Richard, F Ader, M Roux, E Donal, JC Eicher… - Clinical …, 2019 - Wiley Online Library
Left ventricular non‐compaction (LVNC) is a cardiomyopathy that may be of genetic origin;
however, few data are available about the yield of mutation, the spectrum of genes and …

A wide and specific spectrum of genetic variants and genotype–phenotype correlations revealed by next‐generation sequencing in patients with left ventricular …

C Wang, Y Hata, K Hirono, A Takasaki… - Journal of the …, 2017 - Am Heart Assoc
Background Left ventricular noncompaction (LVNC) has since been classified as a primary
genetic cardiomyopathy, but the genetic basis is not fully evaluated. The aim of the present …

[HTML][HTML] Genetic profile of left ventricular noncompaction cardiomyopathy in children—a single reference center experience

D Piekutowska-Abramczuk, A Paszkowska, E Ciara… - Genes, 2022 - mdpi.com
Background: Left ventricular noncompaction cardiomyopathy (LVNC) is a rare cardiac
disorder characterised by the presence of a two-layer myocardium with prominent …

Genetic spectrum of left ventricular non-compaction in paediatric patients

T Vershinina, Y Fomicheva, A Muravyev, J Jorholt… - Cardiology, 2020 - karger.com
Introduction: Left ventricular non-compaction (LVNC) represents a genetically
heterogeneous cardiomyopathy which occurs in both children and adults. Its genetic …

The importance of genetic counseling, DNA diagnostics, and cardiologic family screening in left ventricular noncompaction cardiomyopathy

YM Hoedemaekers, K Caliskan, M Michels… - Circulation …, 2010 - Am Heart Assoc
Background—Left ventricular (LV) noncompaction (LVNC) is a distinct cardiomyopathy
featuring a thickened bilayered LV wall consisting of a thick endocardial layer with …