Biomarker discovery in neurodegenerative diseases: a proteomic approach
Biomarkers for neurodegenerative disorders are essential to facilitate disease diagnosis,
ideally at early stages, monitor disease progression, and assess response to existing and …
ideally at early stages, monitor disease progression, and assess response to existing and …
Blood-based protein biomarkers for diagnosis and classification of neurodegenerative diseases: current progress and clinical potential
Biomarker research is a rapidly advancing field in medicine. Recent advances in genomic,
genetic, epigenetic, neuroscientific, proteomic, and metabolomic knowledge and …
genetic, epigenetic, neuroscientific, proteomic, and metabolomic knowledge and …
Proteomics of neurodegenerative diseases: analysis of human post‐mortem brain
KW Li, AB Ganz, AB Smit - Journal of neurochemistry, 2019 - Wiley Online Library
Dementias are prevalent brain disorders in the aged population. Dementias pose major
socio‐medical burden, but currently there is no cure available. Novel proteomics …
socio‐medical burden, but currently there is no cure available. Novel proteomics …
Proteomics of human neurodegenerative diseases
The technology, experimental approaches, and bioinformatics that support proteomic
research are evolving rapidly. The application of these new capabilities to the study of …
research are evolving rapidly. The application of these new capabilities to the study of …
Clinical proteomics in neurodegenerative disorders
H Zetterberg, U Rüetschi, E Portelius… - Acta Neurologica …, 2008 - Wiley Online Library
Neurodegenerative disorders are characterized by neuronal impairment that eventually
leads to neuronal death. In spite of the brain's known capacity for regeneration, lost neurons …
leads to neuronal death. In spite of the brain's known capacity for regeneration, lost neurons …
Proteomic biomarker discovery in cerebrospinal fluid for neurodegenerative diseases
J Zhang, DR Goodlett… - Journal of Alzheimer's …, 2005 - content.iospress.com
The clinical diagnosis of major neurodegenerative disorders, eg Alzheimer's disease,
Parkinson's disease, and dementia with Lewy body, remains unsatisfactory based on current …
Parkinson's disease, and dementia with Lewy body, remains unsatisfactory based on current …
Multiplexing biomarker methods, proteomics and considerations for Alzheimer's disease
RAS Robinson, B Amin, PC Guest - Proteomic methods in …, 2017 - Springer
Biomarker research for Alzheimer's disease (AD) has been growing rapidly over recent
years especially as the number of persons affected by this disease is nearing approximately …
years especially as the number of persons affected by this disease is nearing approximately …
Proteomics of human cerebrospinal fluid–the good, the bad, and the ugly
J Zhang - Proteomics–Clinical Applications, 2007 - Wiley Online Library
The development of MALDI ESI in the late 1980s has revolutionized the biological sciences
and facilitated the emergence of a new discipline called proteomics. Application of …
and facilitated the emergence of a new discipline called proteomics. Application of …
Proteomics in neurodegeneration–disease driven approaches
T Schulenborg, O Schmidt, A Van Hall… - Journal of neural …, 2006 - Springer
Proteins as a product from genetic information execute and determine how development,
growth, aging and disease factors are orchestrated within the lifetime of an organism …
growth, aging and disease factors are orchestrated within the lifetime of an organism …
Biomarkers of neurodegenerative diseases: biology, taxonomy, clinical relevance, and current research status
D Koníčková, K Menšíková, L Tučková, E Hényková… - Biomedicines, 2022 - mdpi.com
The understanding of neurodegenerative diseases, traditionally considered to be well-
defined entities with distinguishable clinical phenotypes, has undergone a major shift over …
defined entities with distinguishable clinical phenotypes, has undergone a major shift over …
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