Proteomic technologies for biomarker studies in psychiatry: advances and needs

D Martins-de-Souza, PC Guest… - International review of …, 2011 - Elsevier
In the postgenome era, proteomics has arisen as a promising tool for more complete
comprehension of diseases and for biomarker discovery. Some of these objectives have …

[HTML][HTML] Are blood-based protein biomarkers for Alzheimer's disease also involved in other brain disorders? A systematic review

JTW Chiam, RJB Dobson, SJ Kiddle… - Journal of Alzheimer's …, 2015 - content.iospress.com
Background: Alzheimer's disease (AD) biomarkers are urgently needed for both early and
accurate diagnosis and prediction of disease progression. Past research has studied blood …

Post-translational modifications in Alzheimer's disease and the potential for new biomarkers

CL Russell, S Koncarevic… - Journal of Alzheimer's …, 2014 - content.iospress.com
The ability to detect and diagnose Alzheimer's disease (AD) early is an ever pressing issue,
and the development of markers of disease progression that are able to distinguish AD …

Plasma proteomics for the identification of Alzheimer disease

LH Guo, P Alexopoulos, S Wagenpfeil… - Alzheimer Disease & …, 2013 - journals.lww.com
Less-invasive biomarkers for early Alzheimer disease (AD) are urgently needed. The
present study aimed to establish a panel of plasma proteins that accurately distinguishes …

Quantification of the brain proteome in Alzheimer's disease using multiplexed mass spectrometry

S Musunuri, M Wetterhall, M Ingelsson… - Journal of proteome …, 2014 - ACS Publications
We have compared the brain proteome in the temporal neocortex between Alzheimer's
disease (AD) patients and non-AD individuals by using shotgun mass spectrometry based …

Identification of blood-based biomarkers for diagnosis and prognosis of Parkinson's disease: A systematic review of proteomics studies

SS Chelliah, S Bhuvanendran, KB Magalingam… - Ageing Research …, 2022 - Elsevier
Abstract Parkinson's Disease (PD), a neurodegenerative disorder, is characterised by the
loss of motor function and dopamine neurons. Therapeutic avenues remain a challenge due …

[HTML][HTML] Blood-based proteomic biomarkers of Alzheimer's disease pathology

AL Baird, S Westwood, S Lovestone - Frontiers in neurology, 2015 - frontiersin.org
The complexity of Alzheimer's disease (AD) and its long prodromal phase poses challenges
for early diagnosis and yet allows for the possibility of the development of disease modifying …

Neurochemical dementia diagnostics: state of the art and research perspectives

P Lewczuk, J Wiltfang - Proteomics, 2008 - Wiley Online Library
The aim of this review is to present current state of the art on the field of routine
neurochemical dementia diagnostics (NDD) with a focus on cerebrospinal fluid (CSF) …

[HTML][HTML] Unbiased approaches to biomarker discovery in neurodegenerative diseases

AS Chen-Plotkin - Neuron, 2014 - cell.com
Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease,
amyotrophic lateral sclerosis, and frontotemporal dementia have several important features …

Biomarkers in neurodegenerative diseases

A Jeromin, R Bowser - Neurodegenerative diseases: pathology …, 2017 - Springer
The past decade has seen tremendous efforts in biomarker discovery and validation for
neurodegenerative diseases. The source and type of biomarkers has continued to grow for …