Baicalin, a potent anti-oxidative and anti-inflammatory flavonoid compound derived from
Scutellaria baicalensis, has emerged as a neuroprotective agent. However, the mechanisms …

Parkinson's disease (PD) is one of the most prevalent neurodegenerative disorders with no
precise etiology. Multiple lines of evidence support that environmental factors, either …

Baicalein, a major bioactive flavone constituent isolated from Scutellaria baicalensis Georgi,
has neuroprotective properties in several neurological disorders. Many studies suggest that …

Ethnopharmacological relevance Neuroinflammation, oxidative stress, and protein
aggregation form a vicious cycle in the pathophysiology of Parkinson's disease (PD); …

The NLR family pyrin domain containing 3 (NLRP3) inflammasome was reported to be
regulated by autophagy and activated during inflammatory procession of Parkinson's …

Baicalin (BA) is a major flavone from Scutellaria baicalensis Georgi and has showed
significant curative effects in Parkinson's and Alzheimer's diseases. In the present study, we …

Baicalein, one of the major flavonoids found in Scutellaria baicalensis Georgi, displays
neuroprotective effects on experimental models of Parkinson's disease (PD) in vitro and in …

Parkinson's disease (PD) is a neurodegenerative disease characterized by the gradual loss
of dopaminergic (DA) neurons in the substantia nigra (SN) and the formation of intracellular …

Background Inflammasome-induced neuroinflammation is a major pathogenic mechanism
underlying the degeneration of nigral dopaminergic neurons in Parkinson's disease (PD) …

Baicalein, a major bioactive flavone constituent isolated from Scutellaria baicalensis Georgi,
has been shown to be neuroprotective in several Parkinson's disease (PD) animal models …