The CD95 ligand is involved as a death factor in the regulation of activation-induced cell
death, establishment of immune privilege and tumor cell survival. In addition, CD95L may …

Since the ligand for the death factor CD95 (CD95L) was identified almost a decade ago, it
has been established that this molecule (CD95L, FasL, Apo-1L, CD178, TNFSF6, APT1LG1) …

The CD95 Receptor: Apoptosis Revisited: Cell Skip to Main Content Advertisement Cell This
journal offers authors two options (open access or subscription) to publish research Submit Log …

Apoptosis is a fundamental process that contributes to tissue homeostasis, immune
responses, and development. The receptor CD95, also called Fas, is a member of the tumor …

Cell death plays a pivotal role in the maintenance of tissue homeostasis. Key players in the
controlled induction of cell death are the Death Receptors (DR). CD95 is a prototypic DR …

Although the interaction of CD95L (also known as FasL) with its so-called death receptor
CD95 (Fas) induces an apoptotic signal responsible for the elimination of infected and …

CD95 is a dual-function receptor that exerts pro-or antiapoptotic effects depending on the
cellular context, the state of activation, the signal threshold and the mode of ligation. In this …

The ability of FasL/CD95L to induce apoptosis in various Fas/CD95-expressing cells has
been described in the context of hematopoiesis or thymic elimination of self-reactive T cells …

The CD95/Fas/Apo-1 ligand is expressed on activated lymphocytes, NK cells, platelets,
certain immune-privileged cells and some tumor cells and induces apoptosis through the …

CD95 (APO-1, Fas) is a member of the tumor necrosis factor (TNF) receptor superfamily
expressed in various tissues; however, expression of its ligand CD95L, a type II …