Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters

S Yuan, ZW Ye, R Liang, K Tang, AJ Zhang, G Lu… - Science, 2022 - science.org
The in vivo pathogenicity, transmissibility, and fitness of the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) Omicron (B. 1.1. 529) variant are not well …

Neutralization of SARS-CoV-2 Omicron by BNT162b2 mRNA vaccine–elicited human sera

A Muik, BG Lui, AK Wallisch, M Bacher, J Mühl… - Science, 2022 - science.org
The globally circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variant of concern Omicron (B. 1.1. 529) has a large number of mutations, especially in the …

[HTML][HTML] Attenuated replication and pathogenicity of SARS-CoV-2 B. 1.1. 529 Omicron

H Shuai, JFW Chan, B Hu, Y Chai, TTT Yuen, F Yin… - Nature, 2022 - nature.com
Abstract The Omicron (B. 1.1. 529) variant of SARS-CoV-2 emerged in November 2021 and
is rapidly spreading among the human population. Although recent reports reveal that the …

[PDF][PDF] Reduced pathogenicity of the SARS-CoV-2 omicron variant in hamsters

K McMahan, V Giffin, LH Tostanoski, B Chung… - Med, 2022 - cell.com
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron
(B. 1.1. 529) variant has proven to be highly transmissible and has outcompeted the Delta …

[HTML][HTML] SARS-CoV-2 Omicron variant replication in human bronchus and lung ex vivo

KPY Hui, JCW Ho, M Cheung, K Ng, RHH Ching, K Lai… - Nature, 2022 - nature.com
The emergence of SARS-CoV-2 variants of concern with progressively increased
transmissibility between humans is a threat to global public health. The Omicron variant of …

[HTML][HTML] Activity of convalescent and vaccine serum against SARS-CoV-2 Omicron

JM Carreño, H Alshammary, J Tcheou, G Singh… - Nature, 2022 - nature.com
Abstract The Omicron (B. 1.1. 529) variant of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) was initially identified in November 2021 in South Africa and Botswana, as …

[HTML][HTML] SARS-CoV-2 Omicron variant causes mild pathology in the upper and lower respiratory tract of hamsters

F Armando, G Beythien, FK Kaiser, L Allnoch… - Nature …, 2022 - nature.com
Since its discovery in 2019, multiple variants of severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) have been identified. This study investigates virus spread and …

[HTML][HTML] The omicron (B. 1.1. 529) SARS-CoV-2 variant of concern does not readily infect Syrian hamsters

R Abdelnabi, CS Foo, X Zhang, V Lemmens, P Maes… - Antiviral research, 2022 - Elsevier
The emergence of SARS-CoV-2 variants of concern (VoCs) has exacerbated the COVID-19
pandemic. End of November 2021, a new SARS-CoV-2 variant namely the omicron (B. 1.1 …

[HTML][HTML] Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant

R Suzuki, D Yamasoba, I Kimura, L Wang, M Kishimoto… - Nature, 2022 - nature.com
The emergence of the Omicron variant of SARS-CoV-2 is an urgent global health concern. In
this study, our statistical modelling suggests that Omicron has spread more rapidly than the …

Omicron spike function and neutralizing activity elicited by a comprehensive panel of vaccines

JE Bowen, A Addetia, HV Dang, C Stewart, JT Brown… - Science, 2022 - science.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of
concern comprises several sublineages, with BA. 2 and BA. 2.12. 1 having replaced the …